ArticleBioactive materials2019
Powder metallurgical Ti-Mg metal-metal composites facilitate osteoconduction and osseointegration for orthopedic application.
Article in Bioactive materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Fabrication and Characterization of Biomedical Ti-Mg Composites via Spark Plasma Sintering.Materials (Basel, Switzerland) · 2024Article
- Enhancing the immunomodulatory osteogenic properties of Ti-Mg alloy by MgRegenerative biomaterials · 2024Article
- Combining Mg-Zn-Ca Bulk Metallic Glass with a Mesoporous Silica Nanocomposite for Bone Tissue Engineering.Pharmaceutics · 2022Article
- Biodegradability and Cytocompatibility of 3D-Printed Mg-Ti Interpenetrating Phase Composites.Frontiers in bioengineering and biotechnology · 2022Article
- Implantable PEKK/tantalum microparticles composite with improved surface performances for regulating cell behaviors, promoting bone formation and osseointegration.Bioactive materials · 2021Article
- Are Titania Photocatalysts and Titanium Implants Safe? Review on the Toxicity of Titanium Compounds.Nanomaterials (Basel, Switzerland) · 2020Review
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5 authors.
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Abstract
In this work, Ti-Mg metal-metal composites (MMCs) were successfully fabricated by spark plasma sintering (SPS). In vitro, the proliferation and differentiation of SaOS-2 cells in response to Ti-Mg metal-metal composites (MMCs) were investigated. In vivo, a rat model with femur condyle defect was employed, and Ti-Mg MMCs implants were embedded into the femur condyles. Results showed that Ti-Mg MMCs exhibited enhanced cytocompatibility to SaOS-2 cells than pure Ti. The micro-computed tomography (Micro-CT) results showed that the volume of bone trabecula was significantly more abundant around Ti-Mg implants than around Ti implants, indicating that more active new-bone formed around Ti-Mg MMCs implants. Hematoxylin-eosin (H&E) staining analysis revealed significantly greater osteointegration around Ti-Mg implants than that around Ti implants.
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