Evidence map›Paper›PMID 30560199›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2018

Opioid use and the presence of Alzheimer's disease and related dementias among elderly Medicare beneficiaries diagnosed with chronic pain conditions.

Chan Shen, Xiaohui Zhao, Nilanjana Dwibedi, R Constance Wiener, Patricia A Findley, Usha Sambamoorthi

Registry-linked trialAbstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07303998 (Feasibility and Effect of Remotely Supervised Transcranial Direct Current Stimulation With Chair Yoga for Chronic Knee Pain Management in Older Adults With Alzheimer's Disease and Related Dementias.), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07303998 narecruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility and Effect of Remotely Supervised Transcranial Direct Current Stimulation With Chair Yoga for Chronic Knee Pain Management in Older Adults With Alzheimer's Disease and Related Dementias.

TypeinterventionalSponsorUniversity of ArizonaRan2025 to 2026Enrolled40ConditionsAlzheimer&Amp, #39, s Disease, Other DementiasArmsActive tDCS paired with active online chair yoga
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Hospital Admissions Associated With Cancer Pain in Older Adults With and Without Dementia.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Time Trends in Opioid Use by Dementia Severity in Long-Term Care Nursing Home Residents.Journal of the American Medical Directors Association · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Risk Factors for Cardiovascular Events in Patients on Antidementia Medications.American journal of Alzheimer's disease and other dementias
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chan ShenDepartments of Health Services Research and Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Xiaohui ZhaoDepartment of Pharmaceutical Systems and Policy, West Virginia University School of Pharmacy, Robert C. Byrd Health Sciences Center [North], Morgantown, WV, USA.
Nilanjana DwibediDepartment of Pharmaceutical Systems and Policy, West Virginia University School of Pharmacy, Robert C. Byrd Health Sciences Center [North], Morgantown, WV, USA.
R Constance WienerDepartment of Dental Practice and Rural Health, School of Dentistry, West Virginia University, Morgantown, WV, USA.
Patricia A FindleyRutgers University, School of Social Work, New Brunswick, NJ, USA.
Usha SambamoorthiDepartment of Pharmaceutical Systems and Policy, West Virginia University School of Pharmacy, Robert C. Byrd Health Sciences Center [North], Morgantown, WV, USA.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

introductionThere is scant literature on the use of opioids among community-dwelling elderly with Alzheimer's disease and related dementias (ADRD).

methodsWe adopted a retrospective, cross-sectional study design using Medicare Current Beneficiary Survey data from 2006 to 2013. The study sample included elderly community-dwelling Medicare beneficiaries who were diagnosed with chronic pain conditions and had Medicare fee-for-service plans for the entire year. We conducted bivariate χ

resultsThe study sample included 19,347 Medicare beneficiaries; 7.7% of them had ADRD. We found no statistically significant difference in opioid use by ADRD status in the unadjusted analysis; however, controlling for various factors, those with ADRD had lower odds of opioid use (adjusted odds ratio = 0.81, 95% confidence interval = 0.71, 0.93) than those without ADRD. DISCUSSION: This population-based study suggests that elderly Medicare beneficiaries with ADRD and chronic pain conditions may have undertreatment of pain.

Indexed as

Alzheimer's disease and related dementiasChronic pain conditionsElderly populationMedicareOpioid use

Identifiers

PMID30560199
PMCPMC6288458

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.