Evidence map›Paper›PMID 30560146›Full record

ArticleBio-protocol2018

A Modified Barnes Maze for Juvenile Rats.

Nazanin Valibeigi, Daniel G McHail, Carmen L Kimball, Theodore C Dumas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nazanin ValibeigiKrasnow Institute for Advanced Study, George Mason University, Fairfax, VA, USA.
Daniel G McHailKrasnow Institute for Advanced Study, George Mason University, Fairfax, VA, USA.
Carmen L KimballKrasnow Institute for Advanced Study, George Mason University, Fairfax, VA, USA.
Theodore C DumasKrasnow Institute for Advanced Study, George Mason University, Fairfax, VA, USA.

Funding

Postnatal maturation: A model to study hippocampal aging and Alzheimer's diseaseR15AG060461 · NIA · GEORGE MASON UNIVERSITY · PI DUMAS, THEODORE C · 2018 to 2018
$471k
Postnatal functional biomarkers of hippocampal integrity in adulthood and agingR15AG045820 · NIA · GEORGE MASON UNIVERSITY · PI DUMAS, THEODORE C · 2014 to 2014
$352k
NIA NIH HHS R15 AG045820NIA NIH HHS R15 AG060461
6 · The paper itself

Abstract

To better understand neural codes for spatial navigation and to address cognitive development questions, the neurobiology of postnatal hippocampal development is receiving increased attention. While the Morris Water Maze is the gold standard for assessing hippocampal integrity, potential confounds can be difficult to control for in juvenile rodents (around three weeks of age, when spatial navigation ability first emerges) and this wet maze is not amenable to electrophysiological recording. A dry maze alternative with minimal training, like the Barnes Maze adapted for juvenile rats, can help overcome these obstacles. This paper describes in detail the experimental procedure and data analyses for the adapted Barnes maze for juvenile animals.

Indexed as

Barnes mazeDevelopmentDry-land mazeHippocampusJuvenileLearning and memoryProtocolSpatial navigation

Identifiers

PMID30560146
PMCPMC6294133

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.