Evidence map›Paper›PMID 30559974›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Self-report sleep quality combined with sleep time variability distinguishes differences in fatigue, anxiety, and depression in individuals with multiple sclerosis: A secondary analysis.

Catherine F Siengsukon, Mohammed Alshehri, Mayis Aldughmi

Open access · goldAbstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Sleep quality and lymphedema in breast cancer survivors: a mixed method analysis.Journal of cancer survivorship : research and practice · 2025
    Article
  4. Article
  5. Discrepancies between self-reported and device-measured sleep parameters in adults with multiple sclerosis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  6. A multidimensional approach to sleep health in multiple sclerosis.Multiple sclerosis and related disorders · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Catherine F SiengsukonDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, USA.ORCID https://orcid.org/0000-0002-7706-6804
Mohammed AlshehriDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, USA.
Mayis AldughmiDepartment of Physiotherapy, The University of Jordan, Jordan.
University of Kansas Medical Center · USUniversity of Jordan · JO

Funding

Heartland Institute for Clinical and Translational ResearchUL1TR000001 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2012 to 2015
$13.0M
HEARTLAND INSTITUTE FOR CLINICAL AND TRANSLATIONAL RESEARCHUL1RR033179 · NCRR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2011 to 2011
$3.2M
Examining Vascular Regulation Following Acute StrokeK01HD067318 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BILLINGER, SANDRA A · 2011 to 2015
$505k
NCATS NIH HHS UL1 TR000001NCRR NIH HHS UL1 RR033179NICHD NIH HHS K01 HD067318
6 · The paper itself

Abstract

backgroundNearly 70% of individuals with multiple sclerosis report sleep disturbances or poor sleep quality. Sleep disturbances may exacerbate or complicate the management of multiple sclerosis-related symptoms. While sleep variability has been associated with several health outcomes, it is unclear how sleep variability is associated with multiple sclerosis-related symptoms.

objectiveThe purpose of this study was to determine how total sleep time variability combined with self-reported sleep quality is associated with fatigue, depression, and anxiety in individuals with multiple sclerosis.

methodsThis study involved a secondary analysis of actigraphy data and questionnaires to assess sleep quality, fatigue, anxiety, and depression.

resultsThere were significant differences between the Good Sleepers (good sleep quality/low sleep time variability;

conclusionThese results indicate different factors are associated with poor sleep quality in individuals with low versus high total sleep time variability. Considering the factors that are associated with sleep quality and variability may allow for better tailoring of interventions aimed at improving sleep issues or comorbid conditions.

Indexed as

anxietydepressionfatiguemultiple sclerosisSleep qualitysleep variability

Identifiers

PMID30559974
PMCPMC6293381
OpenAlexW2903936424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.