Evidence map›Paper›PMID 30559930›Full record

ArticleOncotarget2018

Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression.

Marie Simonneau, Eric Frouin, Vincent Huguier, Cynthia Jermidi, Jean François Jégou, Julie Godet, Anne Barra, Isabelle Paris, Pierre Levillain, Sevda Cordier-Dirikoc and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. RNA-Sequencing Reveals Two Subgroups of Eccrine Porocarcinomas and Poromas.Journal of cellular and molecular medicine · 2026
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  11. Neutrophils in cancer-unresolved questions.Science China. Life sciences · 2021
    Review
  12. Review
  13. The Tumor Microenvironment in SCC: Mechanisms and Therapeutic Opportunities.Frontiers in cell and developmental biology · 2021
    Review
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Marie SimonneauLITEC, Université de Poitiers, Poitiers, France.
Eric FrouinLITEC, Université de Poitiers, Poitiers, France.
Vincent HuguierLITEC, Université de Poitiers, Poitiers, France.
Cynthia JermidiLITEC, Université de Poitiers, Poitiers, France.
Jean François JégouLITEC, Université de Poitiers, Poitiers, France.
Julie GodetCHU de Poitiers, Poitiers, France.
Anne BarraLITEC, Université de Poitiers, Poitiers, France.
Isabelle ParisLITEC, Université de Poitiers, Poitiers, France.
Pierre LevillainCHU de Poitiers, Poitiers, France.
Sevda Cordier-DirikocBioalternatives, Gençay, France.
Nathalie PedrettiBioalternatives, Gençay, France.
François Xavier BernardLITEC, Université de Poitiers, Poitiers, France.
Jean Claude LecronLITEC, Université de Poitiers, Poitiers, France.
Franck MorelLITEC, Université de Poitiers, Poitiers, France.
Laure FavotLITEC, Université de Poitiers, Poitiers, France.
Université de Poitiers · FRCentre Hospitalier Universitaire de Poitiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous squamous cell carcinoma (cSCC) is the second most common keratinocyte malignancy and accounts for 20% of skin cancer deaths. Cancer is closely related to inflammation, but the contribution of the tumor microenvironment to cSCC development is poorly understood. We previously showed that oncostatin M (OSM), a cytokine belonging to the IL-6 family, promotes normal keratinocyte proliferation and migration, skin inflammation, and epidermal hyperplasia, both

Indexed as

cytokineimmunotherapyoncostatin Mskin cancertumor microenvironment

Identifiers

PMID30559930
PMCPMC6284862
OpenAlexW2901257477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.