ArticlePakistan journal of medical sciences
The role of complete blood inflammation markers in the prediction of spontaneous abortion.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The Predictive Significance of Platelet-to-Lymphocyte Ratio for Miscarriage: A Systematic Review and Meta-Analysis.Immunity, inflammation and disease · 2025Pooled it
- The predictive value of neutrophil to lymphocyte ratio for abortion: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Diagnostic value of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio to predict recurrent pregnancy loss and abortion; a systematic review and meta-analysis.Immunity, inflammation and disease · 2024Pooled it
- First-Trimester CBC-Derived Inflammatory Indices for Prediction of Miscarriage: A Retrospective Cohort Study.Journal of clinical laboratory analysis · 2026Article
- Comparison of first trimester complete blood count parameters in missed abortion and healthy pregnant women: a retrospective case-control study.BMC pregnancy and childbirth · 2026Article
- Blood-based biomarker discovery for early pregnancy loss using integrative multi-omics strategies.EBioMedicine · 2026Article
- Evaluation of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Biomarkers in Missed Abortions.Saudi medical journal · 2026Article
- What affects natural killer cell activity: a cross-sectional study.Frontiers in immunology · 2026Article
- Evaluating the predictive value of systemic inflammation indices in early pregnancy loss: a retrospective observational study.BMC immunology · 2025Observational
- Building a machine learning-based risk prediction model for second-trimester miscarriage.BMC pregnancy and childbirth · 2024Article
- Review
- Platelet to lymphocyte and neutrophil to lymphocyte ratio in the first trimester of pregnancy, are they useful for predicting spontaneous miscarriage? A case-control study.International journal of reproductive biomedicine · 2023Article
- Predictive value of NLR and PLR in missed miscarriage.Journal of clinical laboratory analysis · 2022Article
- Relationship between platelet activation markers and spontaneous abortion: A meta-analysis.Open life sciences · 2022Review
- Does the fibrinogen/albumin ratio predict the prognosis of pregnancies with abortus imminens?Saudi medical journal · 2021Observational
- Kisspeptin and Hematologic Parameters as Predictive Biomarkers for First-Trimester Abortions.Medeniyet medical journal · 2021Article
- Platelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio in Missed Abortion.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2020Article
- The benefits of higher LMR for early threatened abortion: A retrospective cohort study.PloS one · 2020Article
- Analysis of blood coagulation indexes, thromboelastogram and autoantibodies in patients with recurrent pregnancy loss.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate relationships between spontaneous abortion and complete blood count inflammation markers and their role in predicting spontaneous abortion.
methodsThis study was conducted at Department of Obstetrics and Gynecology between January 2012 and January 2017. A total of 570 participants, 325 diagnosed with spontaneous abortion and 245 control patients who underwent timely births were included into our study. The complete blood count inflammation markers included white blood cell (WBC), neutrophil (N), lymphocyte (L), neutrophil-lymphocyte ratio (NLR), mean platelet volume (MPV) and platelet-lymphocyte ratio level (PLR) were recorded.
resultsThere was difference between the abortion groups and control groups in terms of complete blood count (CBC) inflammation markers, including WBC, PLT, neutrophil, lymphocyte, NLR, PLR, and MPV. We found decreased MPV, PLR levels and increased N, L and NLR in the first. and second. Abortion groups compared with the control group. WBC, N, L and NLR were positive predictive markers, and albeit with low sensitivity and specificity, MPV, PLR were found to be a negative predictive marker for the evaluation of spontaneous abortion.
conclusionsUnlike several difficult and invasive tests, a CBC is a simple, inexpensive and easily available test. CBC inflammation markers, including WBC, N, L, NLR, PLR, and MPV, which were evaluated at the sixth gestational week, can be used for the risk assessment of spontaneous abortion in pregnancy.
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