Evidence map›Paper›PMID 30559743›Full record

ReviewFrontiers in immunology2018

Current State of Dendritic Cell-Based Immunotherapy: Opportunities for

Anne Huber, Floris Dammeijer, Joachim G J V Aerts, Heleen Vroman

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Targeting the EphA2 pathway: could it be the way for bone sarcomas?Cell communication and signaling : CCS · 2024
    Review
  12. Review
  13. Cracking the Codes behind Cancer Cells' Immune Evasion.International journal of molecular sciences · 2024
    Review
  14. Article
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  18. Review
  19. Article
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anne HuberDepartment of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands.
Floris DammeijerDepartment of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands.
Joachim G J V AertsDepartment of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands.
Heleen VromanDepartment of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cell (DC) based cancer immunotherapy aims at the activation of the immune system, and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor. DCs represent a heterogeneous cell population, including conventional DCs (cDCs), consisting of cDC1s, cDC2s, plasmacytoid DCs (pDCs), and monocyte-derived DCs (moDCs). These DC subsets differ both in ontogeny and functional properties, such as the capacity to induce CD4

Indexed as

AnimalsAntigen PresentationCancer VaccinesDendritic CellsHumansImmunotherapyLymphocyte ActivationMonocytesNeoplasmsT-Lymphocytes, CytotoxicTumor MicroenvironmentCancer VaccinesDC subsetsdendritic cell (DC)ImmunotherapyT cell responsestumor immunology

Identifiers

PMID30559743
PMCPMC6287551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.