Evidence map›Paper›PMID 30559223›Full record

ArticleInfection and immunity2019

Toll-like Receptor 2 Prevents Neutrophil-Driven Immunopathology during Infection with Mycobacterium tuberculosis by Curtailing CXCL5 Production.

Archana Gopalakrishnan, Jillian Dietzold, Sheetal Verma, Madhuri Bhagavathula, Padmini Salgame

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. LncRNA DANCR restrained the survival ofFrontiers in microbiology · 2023
    Article
  6. Different modalities of host cell death and their impact onAmerican journal of physiology. Cell physiology · 2022
    Review
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  9. Article
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  12. Article
  13. Article
  14. The Immune Escape Mechanisms ofInternational journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Archana Gopalakrishnan *Rutgers-New Jersey Medical School, Newark, New Jersey, USA.
Jillian Dietzold *Rutgers-New Jersey Medical School, Newark, New Jersey, USA.
Sheetal VermaRutgers-New Jersey Medical School, Newark, New Jersey, USA.
Madhuri BhagavathulaRutgers-New Jersey Medical School, Newark, New Jersey, USA.
Padmini SalgameRutgers-New Jersey Medical School, Newark, New Jersey, USA padmini.salgame@rutgers.edu.
Rutgers New Jersey Medical SchoolRutgers, The State University of New Jersey · US

Funding

BD Facsaria for use in BSL3S10RR025465 · NCRR · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI SALGAME, PADMINI · 2009 to 2009
$465k
NCRR NIH HHS S10 RR025465
6 · The paper itself

Abstract

The W-Beijing strain family is globally distributed and is associated with multidrug-resistant tuberculosis (TB) and treatment failure. Therefore, in this study, we examined the contribution of Toll-like receptor 2 (TLR2) to host resistance against

Indexed as

AnimalsChemokine CXCL5FemaleGene Expression RegulationInflammationMiceMice, Inbred C57BLMice, KnockoutMycobacterium tuberculosisNeutrophilsSpecific Pathogen-Free OrganismsToll-Like Receptor 2TuberculosisChemokine CXCL5Cxcl5 protein, mouseTlr2 protein, mouseToll-Like Receptor 2CXCL5immunopathologyinflammationMycobacterium tuberculosisneutrophilsTLR2

Identifiers

PMID30559223
PMCPMC6386542
OpenAlexW2903661635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.