Evidence map›Paper›PMID 30559201›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Catalyst discovery through megalibraries of nanomaterials.

Edward J Kluender, James L Hedrick, Keith A Brown, Rahul Rao, Brian Meckes, Jingshan S Du, Liane M Moreau, Benji Maruyama, Chad A Mirkin

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. A General Group Testing Strategy for Discovering Chemical Cooperativity.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Traversing the Periodic Table through Phase-Separating Nanoreactors.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  9. Article
  10. Automated crystal system identification from electron diffraction patterns using multiview opinion fusion machine learning.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Article
  12. Article
  13. Custom-made holey grapheneNanoscale advances · 2022
    Article
  14. Article
  15. Article
  16. A Meta-Analysis of Conductive and Strong Carbon Nanotube Materials.Advanced materials (Deerfield Beach, Fla.) · 2021
    Review
  17. Article
  18. Dip-Pen Nanolithography(DPN): from Micro/Nano-patterns to Biosensing.Chemical research in Chinese universities · 2021
    Review
  19. Article
  20. High-throughput, combinatorial synthesis of multimetallic nanoclusters.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Edward J KluenderDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208.ORCID 0000-0003-0313-2351
James L HedrickInternational Institute for Nanotechnology, Northwestern University, Evanston, IL 60208.ORCID 0000-0002-3968-9728
Keith A BrownInternational Institute for Nanotechnology, Northwestern University, Evanston, IL 60208.ORCID 0000-0002-2379-2018
Rahul RaoMaterials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, OH 45433.
Brian MeckesInternational Institute for Nanotechnology, Northwestern University, Evanston, IL 60208.ORCID 0000-0002-8389-4622
Jingshan S DuDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208.ORCID 0000-0002-4932-6699
Liane M MoreauDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208.
Benji MaruyamaMaterials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, OH 45433.
Chad A MirkinDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208; chadnano@northwestern.edu.ORCID 0000-0002-6634-7627

Funding

Project 3: Spherical Nucleic Acids as Immunotherapeutic Agents for Prostate CancerU54CA199091 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MIRKIN, CHAD A. · 2015 to 2019
$11.7M
NCI NIH HHS U54 CA199091
6 · The paper itself

Abstract

The nanomaterial landscape is so vast that a high-throughput combinatorial approach is required to understand structure-function relationships. To address this challenge, an approach for the synthesis and screening of megalibraries of unique nanoscale features (>10,000,000) with tailorable location, size, and composition has been developed. Polymer pen lithography, a parallel lithographic technique, is combined with an ink spray-coating method to create pen arrays, where each pen has a different but deliberately chosen quantity and composition of ink. With this technique, gradients of Au-Cu bimetallic nanoparticles have been synthesized and then screened for activity by in situ Raman spectroscopy with respect to single-walled carbon nanotube (SWNT) growth. Au

Indexed as

CatalysisSmall Molecule LibrariesCopperGold AlloysHigh-Throughput Screening AssaysMetal NanoparticlesNanostructuresNanotubes, CarbonSpectrum Analysis, RamanCopperGold AlloysNanotubes, CarbonSmall Molecule Librariescarbon nanotube growthcatalysiscombinatorial screeningin situ Raman spectroscopymultimetallic nanoparticle synthesis

Identifiers

PMID30559201
PMCPMC6320520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.