Evidence map›Paper›PMID 30559159›Full record

ArticleBMJ open2018

Early weight gain after stopping smoking: a predictor of overall large weight gain? A single-site retrospective cohort study.

Alexandra Pankova, Eva Kralikova, Kamila Zvolska, Lenka Stepankova, Milan Blaha, Petra Ovesna, Paul Aveyard

Abstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandra PankovaCentre for Tobacco-Dependent, 3rd Medical Department, First Faculty of Medicine, Charles University and the General University Hospital, Charles University, Prague, Czech Republic.
Eva KralikovaCentre for Tobacco-Dependent, 3rd Medical Department, First Faculty of Medicine, Charles University and the General University Hospital, Charles University, Prague, Czech Republic.
Kamila ZvolskaCentre for Tobacco-Dependent, 3rd Medical Department, First Faculty of Medicine, Charles University and the General University Hospital, Charles University, Prague, Czech Republic.
Lenka StepankovaCentre for Tobacco-Dependent, 3rd Medical Department, First Faculty of Medicine, Charles University and the General University Hospital, Charles University, Prague, Czech Republic.
Milan BlahaInstitute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Petra OvesnaInstitute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Paul AveyardNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Funding

Medical Research Council MR/K023195/1
6 · The paper itself

Abstract

objectivesMost people gain weight on stopping smoking but the extent of weight gain varies greatly. Interventions aimed at all quitters to prevent weight gain on cessation have proven unpopular but targeting people who have gained excess weight immediately after quitting may improve uptake and cost-effectiveness. We examined whether early large postcessation weight gain predicts overall large weight gain.

designRetrospective cohort study.

settingPrimary care setting-smoking cessation centre in Prague, Czech Republic.

participantsOut of 3537 patients treated between 2005 and 2013, 1050 were continuous abstainers (verified by carbon monoxide measurement) at 1-year follow-up and formed the cohort of the current report. 48.7% were women (n=511) with the mean age of 46 (±14.4) years.

methodsIn this retrospective cohort study, all patients underwent usual tobacco dependence treatment using evidence-based methods. Weight was measured prior to smoking cessation and at each visit after quitting.

resultsThe mean weight gain in the first month (n=763) was 0.79% (±2.03%), in the second month (n=646) was 1.49% (±2.58%), for the third month (n=566) 2.33% (±3.44%) and 4.1% (±5.31%) after 1-year follow-up (n=1050). The regression coefficient per 1% rise in the first 3 months was +0.13% (95% CI -0.04% to 0.30%). A receiver operating curve analysis showed that patients gaining more than 0.98% of their baseline weight during first 3 months had a sensitivity of 66% and specificity of 44% for gaining 7% or more weight by 12 months. In addition, lower body mass index and an increase in appetite at 3 months after quitting were associated with greater weight gain, while using nicotine replacement therapy was associated with less weight gain at 1-year follow-up.

conclusionsPeople who stop smoking and gain a larger amount of weight early after quitting are not more likely to gain excessively at 1 year.

Indexed as

OverweightSmokingSmoking CessationAdultAppetiteBody Mass IndexCzech RepublicFemaleHumansMaleMiddle AgedNicotinePrognosisRetrospective StudiesSmoking Cessation AgentsWeight GainNicotineSmoking Cessation Agentsbody weight changessmokingsmoking cessationweightweight gain

Identifiers

PMID30559159
PMCPMC6303564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.