SynthesisJournal of endodontics2019
Ultrasonic Irrigant Activation during Root Canal Treatment: A Systematic Review.
Synthesis in Journal of endodontics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 4 syntheses or guidelines pooled it, 149 citations in OpenAlex.
- Comparative Efficacy of Different Irrigant Activation Techniques for Irrigant Delivery Up to the Working Length of Mature Permanent Teeth: A Systematic Review and Meta-Analysis.European endodontic journal · 2023Pooled it
- Pooled it
- Postoperative pain in root canal treatment with ultrasonic versus conventional irrigation: a systematic review and meta-analysis of randomized controlled trials.Clinical oral investigations · 2022Pooled it
- Irrigating Solutions and Activation Methods Used in Clinical Endodontics: A Systematic Review.Frontiers in oral health · 2022Pooled it
- The effect of foraminal enlargement and irrigant activation technique on post-operative pain in necrotic teeth - a clinical study.BMC oral health · 2026Trial
- Randomised Controlled Trial on the Additive Effect Between Calcium Hydroxide and Sodium Hypochlorite in an Inter-Visit Root Canal Dressing.International endodontic journal · 2026Trial
- Efficacy of Continuous Chelation With Etidronate And Sequential Chelation With Chitosan On Bacterial Reduction In Teeth With Pulp Necrosis: A Double-Blind, Randomized Clinical Trial.European endodontic journal · 2025Trial
- Association between the irrigation-agitation techniques and Periapical Healing of large periapical lesions: a Randomized Controlled Trial.Clinical oral investigations · 2024Trial
- Endodontic implications of hypercementosis: A systematic review of anatomical challenges and therapeutic strategies.The Japanese dental science review · 2026Review
- Effects of Sodium Hypochlorite Concentration and Final Irrigation Protocol on Residual Filling Material in Retreated Oval Root Canals Obturated with a Calcium Silicate-Based Sealer: A Scanning Electron Microscopy Study.Medicina (Kaunas, Lithuania) · 2026Article
- Evaluation of bacterial reduction by contemporary irrigation activation methods against Enterococcus faecalis biofilm in root canals.Scientific reports · 2026Article
- Effect of intracanal heating of sodium hypochlorite alone and in combination with ultrasonic activation on postoperative endodontic pain: A randomized clinical trial.Journal of conservative dentistry and endodontics · 2026Article
- Effect of irrigant activation systems and dentine ageing on sealer penetration into dentinal tubules.Brazilian oral research · 2026Article
- Endodontic Diagnosis and Nonsurgical Management of a Maxillary Second Molar With Parastyle: Report of a Case With a 24-Month Follow-Up.Case reports in dentistry · 2026Article
- The effect of the use of irrigation activation methods with different file systems on the amount of apical debris extrusion.Scientific reports · 2025Article
- Influence of passive ultrasonic irrigation cycles on the penetration depth of sodium hypochlorite into root dentin.Scientific reports · 2025Article
- Differences in clinical approaches of endodontists and general dentists when performing non-surgical root canal treatment: A prospective cohort study from the National Dental Practice-Based Research Network PREDICT Project.International endodontic journal · 2025Article
- Exploiting the power of stepwise intraoperative irrigant activation to maximize oval canal disinfection: an ex-vivo investigation.BMC oral health · 2025Article
- Comparisons of the smear layer removal efficacy of dual-action irrigants and different activation techniques.Journal of dental sciences · 2025Article
- Effect of a novel irrigation regimen and root canal filling material versus conventional endodontic protocols on dentin wettability.Odontology · 2025Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this study was to systematically review the evidence on the cleaning and disinfection of root canals and the healing of apical periodontitis when ultrasonic irrigant activation is applied during primary root canal treatment of mature permanent teeth compared with syringe irrigation.
methodsAn electronic search was conducted of the Cochrane Library, Embase, LILACS, PubMed, SciELO, and Scopus databases using both free-text key words and controlled vocabulary. Additional studies were sought through hand searching of endodontic journals and textbooks. The retrieved studies were screened by 2 reviewers according to predefined criteria. The included studies were critically appraised, and the extracted data were arranged in tables.
resultsThe electronic and hand search retrieved 1966 titles. Three clinical studies and 45 in vitro studies were included in this review. Ultrasonic activation did not improve the healing rate of apical periodontitis compared with syringe irrigation after primary root canal treatment of teeth with a single root canal. Conflicting results were reported by the in vitro microbiological studies. Ultrasonic activation was more effective than syringe irrigation in the removal of pulp tissue remnants and hard tissue debris based on both clinical and in vitro studies. Ultrasonic activation groups were possibly favored in 13 studies, whereas syringe irrigation groups may have been favored in 3 studies.
conclusionsThe level of the available evidence was low, so no strong clinical recommendations could be formulated. Future studies should focus on the antimicrobial effect and healing of apical periodontitis in teeth with multiple root canals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.