ArticleParasites & vectors2018
Molecular detection of tick-borne pathogens in canine population and Rhipicephalus sanguineus (sensu lato) ticks from southern Metro Manila and Laguna, Philippines.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Emerging zoonotic diseases in Southeast Asia in the period 2011-2022: a systematic literature review.The veterinary quarterly · 2024Pooled it
- Molecular-Based Detection of Vector-Borne Diseases in Shelter Dogs in Northern of Vietnam.Pathogens (Basel, Switzerland) · 2026Article
- The Comparative Study for Detection of Canine Vector-Borne Pathogens Between Companion and Stray Dogs in Bangkok and Vicinities, Thailand.Pathogens (Basel, Switzerland) · 2026Article
- First molecularly-confirmed canine rickettsiosis in Southern Philippines (Cebu): A case report.Open veterinary journal · 2026Article
- A One-Month Survey on Infestation ofArchives of Razi Institute · 2025Article
- Automated tick classification using deep learning and its associated challenges in citizen science.Scientific reports · 2025Article
- First Evidence ofJournal of parasitology research · 2025Article
- First detection ofFrontiers in veterinary science · 2025Article
- Seasonal dynamic of ticks infesting cattle (Bos indicus) farms in two provinces in Cambodia.PloS one · 2025Article
- Molecular detection of Rickettsia species in ectoparasites collected from two southern provinces of Cambodia.PLoS neglected tropical diseases · 2024Article
- Molecular detection and characterization of Anaplasma marginale and Babesia canis vogeli infecting dogs in Luxor, Egypt.Scientific reports · 2024Article
- Seroprevalence study in humans and molecular detection in Rhipicephalus sanguineus ticks of severe fever with thrombocytopenia syndrome virus in Thailand.Scientific reports · 2024Article
- Molecular detection and characterization ofParasite epidemiology and control · 2024Article
- The detection of zoonotic microorganisms inFrontiers in veterinary science · 2024Article
- Bovine Piroplasma Populations in the Philippines Characterized Using Targeted Amplicon Deep Sequencing.Microorganisms · 2023Article
- Canine Babesiosis Caused by LargeAnimals : an open access journal from MDPI · 2023Review
- Genetic diversity of vector-borne pathogens in ixodid ticks infesting dogs from Pakistan with notes on Ehrlichia canis, Rickettsia raoultii and Dirofilaria immitis detection.Parasites & vectors · 2023Article
- Diversity analysis of the endosymbiotic bacterial community in field-collected Haemaphysalis ticks on the tropical Hainan Island, China.Folia parasitologica · 2023Article
- Molecular Detection and Phylogenetic Characterization ofVeterinary sciences · 2023Article
- Molecular detection ofVeterinary world · 2023Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe tropical climate of the Philippines and the high population of dogs, particularly in cities, favors the life-cycle of the brown dog tick, Rhipicephalus sanguineus (sensu lato), a vector of several canine tick-borne pathogens (TBPs) including zoonotic Rickettsia spp. Suspected cases of infections are commonly encountered in veterinary clinics, but the specific TBPs are rarely identified. Furthermore, infection with Rickettsia is not being clinically examined in dogs. In this study, the occurrence of TBPs in blood and ticks collected from household and impounded dogs in highly populated areas of the Philippines, Metro Manila, and the nearby province of Laguna, was examined.
resultsA total of 248 blood samples and 157 tick samples were subjected to PCR. First, samples were screened using primers for Anaplasma/Ehrlichia spp. and Babesia/Hepatozoon spp. Those that turned positive were further subjected to species-specific PCR. Rickettsia spp. were also detected through a nested PCR. Of the 248 blood samples, 56 (22.6%) were positive for Anaplasma/Ehrlichia spp., while 19 (7.6%) were positive for Babesia/Hepatozoon spp. Species-specific PCR revealed that 61 (23.4%) had a single TBP, with Ehrlichia canis being detected in 39 (15.7%) dogs, while 14 (5.6%) dogs were positive for different combinations of two to four TBPs. Rickettsia infection was detected in 6 (2.4%) dogs. In tick samples, 8 (3.2%) were positive for Ehrlichia/Anaplasma spp., while only 1 (0.63%) was positive for Babesia/Hepatozoon spp. As in the blood samples, E. canis was the most detected, being found in 5 (2%) samples. No tick samples tested positive for Rickettsia spp.
conclusionEhrlichia canis is the most common TBP affecting dogs in the Philippines. Co-infection with TBPs is quite common, hence testing for multiple TBPs is necessary. Through nested PCR, Rickettsia infection was detected in dogs, and to the authors' knowledge, this study provides the first molecular evidence of Rickettsia infection in dogs in the Philippines.
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