Evidence map›Paper›PMID 30558606›Full record

ArticleRespiratory research2018

Pulmonary aspiration in preschool children with cystic fibrosis.

D Clarke, I Gorman, F Ringholz, M McDermott, D W Cox, P Greally, B Linnane, P Mc Nally

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

D ClarkeNational Children's Research Centre, Crumlin, Dublin 12, Ireland.
I GormanNational Children's Research Centre, Crumlin, Dublin 12, Ireland. igorman@tcd.ie.
F RingholzNational Children's Research Centre, Crumlin, Dublin 12, Ireland.
M McDermottOur Lady's Children's Hospital, Crumlin, Dublin 12, Ireland.
D W CoxNational Children's Research Centre, Crumlin, Dublin 12, Ireland.
P GreallyNational Children's Hospital, Tallaght, Dublin, Ireland.
B LinnaneNational Children's Research Centre, Crumlin, Dublin 12, Ireland.
P Mc NallyNational Children's Research Centre, Crumlin, Dublin 12, Ireland.
Children's Health Ireland at Crumlin · IENational Children’s Research Centre · IETallaght University Hospital · IEUniversity of Limerick · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary aspiration of gastric refluxate (PAGR) has been demonstrated in association with pulmonary inflammation in school aged children with Cystic Fibrosis (CF). We sought to determine if similar findings were present in preschool children. Pepsin was measured in Broncho-alveolar lavage (BAL) fluid collected from clinically stable preschool children with CF and controls. Elevated pepsin levels were found in a subgroup of children with CF, but this was not found to be associated with pulmonary infection, pulmonary inflammation or respiratory or gastrointestinal symptoms.

Indexed as

Bronchoalveolar Lavage FluidBronchoalveolar LavageBronchoscopyChildChild, PreschoolCystic FibrosisFemaleGastroesophageal RefluxHumansInfantMaleProspective StudiesRespiratory Aspiration

Identifiers

PMID30558606
PMCPMC6296125
OpenAlexW2904015438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.