ArticleBMC public health2018
The association between self-rated health and high-sensitivity C-reactive protein level: a cross-sectional and 5-year longitudinal study.
Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Self-rated health and inflammation: Associations among partnered sexual minority and heterosexual adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Sleep duration and depressive symptoms among older Chinese adults: a serial mediation model of self-rated health and frailty.BMC geriatrics · 2026Article
- Survival After the First Myocardial Infarction in Older Women: A Prospective Cohort Analysis From the WHI.Journal of the American Heart Association · 2026Article
- Article
- Gender and age variations in the association between multigenerational cohabitation and self-rated health among middle-aged and older adults in Japan.Nagoya journal of medical science · 2024Article
- Association of daily physical activity and leisure-time exercise with dysphagia risk in community-dwelling older adults: a cross-sectional study.Scientific reports · 2023Article
- Association of the number of teeth and self-rated mastication with self-rated health in community-dwelling Japanese aged 40 years and older: the Yamagata cohort study.Scientific reports · 2022Article
- The health status: the ignored risk factor in dementia incidence. NEDICES cohort.Aging clinical and experimental research · 2022Article
- Physical and Psychological Factors Contributing to Incidental Falls in Older Adults Who Perceive Themselves as Unhealthy: A Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- The association between self-compassion and self-rated health in 26 samples.BMC public health · 2020Article
- Assessment of self-rated health 5 years after Roux-en-Y gastric bypass for severe obesity.BJS open · 2019Article
- Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAlthough self-rated health (SRH) independently predicts mortality, the biological background of this association remains unexplained. This study aimed to examine the association between SRH and serum high-sensitivity C-reactive protein (hsCRP) level.
methodsSubjects were 899 participants aged 35-69 years (237 men and 662 women) in the Daiko Study, part of the Japan Multi-Institutional Collaborative Cohort Study. They were enrolled from 2008 to 2010. Of the subjects, 666 participated in a second survey 5 years later. Lifestyle factors and SRH were assessed using a self-administered questionnaire. Serum hsCRP level was measured using a latex-enhanced immunonephelometric assay. The association between SRH and serum hsCRP level was evaluated using a general linear model with covariates. We further longitudinally investigated whether higher serum hsCRP level at baseline predicts poor SRH after 5 years using an unconditional logistic regression model.
resultsA higher serum hsCRP level was significantly associated with poor SRH at baseline after adjusting for covariates (p for trend = 0.023). The age- and sex-adjusted odds ratio and 95% confidence interval (CI) for poor SRH after 5 years was 1.45 (95% CI: 0.76-2.78) for the highest tertile compared with the lowest tertile of serum hsCRP level at baseline with a significant linear trend (p for trend = 0.033), although the risk increase disappeared after adjustment for other covariates.
conclusionsThe present study demonstrated that poor SRH is cross-sectionally associated with higher serum hsCRP level. However, the longitudinal data did not support the relationship between serum hsCRP level at baseline and future SRH. Further longitudinal studies that include data on mortality and multiple inflammatory markers are warranted to elucidate the possible role of low-grade inflammation in the association between SRH and mortality risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.