ArticleInternational journal of environmental research and public health2018
Estimated Residential Exposure to Agricultural Chemicals and Premature Mortality by Parkinson's Disease in Washington State.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Systematic literature review of the epidemiology of glyphosate and neurological outcomes.International archives of occupational and environmental health · 2023Pooled it
- An acute dose of glyphosate alters novel object exploration and hippocampal cFos expression in a sex-dependent manner in wildtype mice.Neuroscience · 2026Article
- DYRK1A and Parkinson's disease, facts and hypotheses.Neurobiology of disease · 2026Review
- Agricultural pesticide use and Alzheimer's disease dementia prevalence across US counties in a mixed supervised-unsupervised analysis.Scientific reports · 2026Article
- Preventing Parkinson's disease in the context of movement disorders: a narrative review of current evidence and future directions.Neurological research and practice · 2026Review
- Review
- Pesticides and parkinson's disease: causal relationship at the population and individual level?Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- A Novel Approach for Colorimetric Detection of Glyphosate in Food Based on a Split Aptamer Nanostructure and DNAzyme Activity.Journal of fluorescence · 2025Article
- Review
- Article
- Environmental Risk Factors for Parkinson's Disease: A Critical Review and Policy Implications.Movement disorders : official journal of the Movement Disorder Society · 2025Review
- The bacterial species' degradation activities at maximum threshold doses of glyphosate across different pH levels and temperature glyphosate biodegradation by soil bacteria at high doses under variable pH and temperature.Frontiers in microbiology · 2025Article
- Parkinson's Disease Progression and Exposure to Contaminated Water at Camp Lejeune.Movement disorders : official journal of the Movement Disorder Society · 2024Article
- Article
- Cluster pattern analysis of environmental stressors and quantifying their impact on all-cause mortality in Belgium.BMC public health · 2024Article
- Impact of glyphosate (RoundupGut microbes · 2023Review
- Long-Term Effects of Perinatal Exposure to a Glyphosate-Based Herbicide on Melatonin Levels and Oxidative Brain Damage in Adult Male Rats.Antioxidants (Basel, Switzerland) · 2023Article
- Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease.NPJ Parkinson's disease · 2023Review
- Pesticides and the Microbiome-Gut-Brain Axis: Convergent Pathways in the Pathogenesis of Parkinson's Disease.Journal of Parkinson's disease · 2023Review
- Why the Gut Microbiome Must Be Considered When Evaluating the Impact of Pesticides on Parkinson's Disease Risk.Journal of Parkinson's disease · 2023Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to examine the relationship between estimated residential exposure to agricultural chemical application and premature mortality from Parkinson's disease (PD) in Washington State. Washington State mortality records for 2011⁻2015 were geocoded using residential addresses, and classified as having exposure to agricultural land-use within 1000 meters. Generalized linear models were used to explore the association between land-use associated with agricultural chemical application and premature mortality from PD. Individuals exposed to land-use associated with glyphosate had 33% higher odds of premature mortality than those that were not exposed (Odds Ratio (OR) = 1.33, 95% Confidence Intervals (CI) = 1.06⁻1.67). Exposure to cropland associated with all pesticide application (OR = 1.19, 95% CI = 0.98⁻1.44) or Paraquat application (OR = 1.22, 95% CI = 0.99⁻1.51) was not significantly associated with premature mortality from PD, but the effect size was in the hypothesized direction. No significant associations were observed between exposure to Atrazine (OR = 1.21, 95% CI = 0.84⁻1.74) or Diazinon (OR = 1.07, 95% CI = 0.85⁻1.34), and premature mortality from PD. The relationship between pesticide exposure and premature mortality aligns with previous biological, toxicological, and epidemiological findings. Glyphosate, the world's most heavily applied herbicide, and an active ingredient in Roundup
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Registered trials
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