Evidence map›Paper›PMID 30558341›Full record

ArticleJournal of clinical medicine2018

One--Year Progression and Risk Factors for the Development of Chronic Kidney Disease in Septic Shock Patients with Acute Kidney Injury: A Single-Centre Retrospective Cohort Study.

June-Sung Kim, Youn-Jung Kim, Seung Mok Ryoo, Chang Hwan Sohn, Dong Woo Seo, Shin Ahn, Kyoung Soo Lim, Won Young Kim

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

June-Sung KimDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. jsmeet09@gmail.com.
Youn-Jung KimDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. yjkim.em@gmail.com.
Seung Mok RyooDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. chrisryoo@naver.com.
Chang Hwan SohnDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. schwan97@gmail.com.
Dong Woo SeoDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. leiseo@gmail.com.
Shin AhnDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. ans1023@gmail.com.
Kyoung Soo LimDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. kslim@amc.seoul.kr.
Won Young KimDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. wonpia73@naver.com.ORCID 0000-0002-6904-5966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Sepsis-associated acute kidney injury (AKI) can lead to permanent kidney damage, although the long-term prognosis in patients with septic shock remains unclear. This study aimed to identify risk factors for the development of chronic kidney disease (CKD) in septic shock patients with AKI. (2) Methods: A single-site, retrospective cohort study was conducted using a registry of adult septic shock patients. Data from patients who had developed AKI between January 2011 and April 2017 were extracted, and 1-year follow-up data were analysed to identify patients who developed CKD. (3) Results: Among 2208 patients with septic shock, 839 (38%) had AKI on admission (stage 1: 163 (19%), stage 2: 339 (40%), stage 3: 337 (40%)). After one year, kidney function had recovered in 27% of patients, and 6% had progressed to CKD. In patients with stage 1 AKI, 10% developed CKD, and mortality was 13% at one year; in patients with stage 2 and 3 AKI, the CKD rate was 6%, and the mortality rate was 42% and 47%, respectively. Old age, female, diabetes, low haemoglobin levels and a high creatinine level at discharge were seen to be risk factors for the development of CKD. (4) Conclusions: AKI severity correlated with mortality, but it did not correlate with the development of CKD, and patients progressed to CKD, even when initial AKI stage was not severe. Physicians should focus on the recovery of renal function, and ensure the careful follow-up of patients with risk factors for the development of CKD.

Indexed as

acute kidney diseaseacute kidney injurychronic kidney diseasefollow-upseptic shock

Identifiers

PMID30558341
PMCPMC6306914

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.