Evidence map›Paper›PMID 30558289›Full record

ArticleToxins2018

Impact of

Harry F Williams, Paul Hayter, Divyashree Ravishankar, Anthony Baines, Harry J Layfield, Lorraine Croucher, Catherine Wark, Andrew B Bicknell, Steven Trim, Sakthivel Vaiyapuri

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Metabolism open · 2022
    Article
  5. Article
  6. Article
  7. Effects of 3FTx Protein Fraction fromMolecules (Basel, Switzerland) · 2021
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Harry F WilliamsSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK. h.f.williams@pgr.reading.ac.uk.
Paul HayterVenomtech, Discovery Park, Sandwich, Kent CT13 9ND, UK. paul.hayter@talktalk.net.
Divyashree RavishankarSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK. d.ravishankar@reading.ac.uk.ORCID 0000-0001-5856-5416
Anthony BainesSchool of Biosciences, University of Kent, Kent CT2 7NZ, UK. a.bains@venomtech.co.uk.
Harry J LayfieldSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK. h.j.layfield@reading.ac.uk.
Lorraine CroucherBMG LabTech, Buckinghamshire HP19 8JR, UK. lorraine.croucher@bmglabtech.com.
Catherine WarkBMG LabTech, Buckinghamshire HP19 8JR, UK. catherine.wark@bmglabtech.com.
Andrew B BicknellSchool of Biological Sciences, University of Reading, Reading RG6 6UB, UK. a.b.bicknell@reading.ac.uk.
Steven TrimVenomtech, Discovery Park, Sandwich, Kent CT13 9ND, UK. s.trim@venomtech.co.uk.
Sakthivel VaiyapuriSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK. s.vaiyapuri@reading.ac.uk.ORCID 0000-0002-6006-6517
University of Reading · GBUniversity of Kent · GB

Funding

British Heart Foundation PG/16/64/32311
6 · The paper itself

Abstract

Snakebite envenomation is an affliction currently estimated to be killing upwards of 100,000 people annually. Snakebite is associated with a diverse pathophysiology due to the magnitude of variation in venom composition that is observed worldwide. The haemolytic (i.e., lysis of red blood cells) actions of snake venoms are well documented, although the direct impact of venoms on haemoglobin is not fully understood. Here we report on the varied ability of a multitude of snake venoms to oxidise haemoglobin into methaemoglobin. Moreover, our results demonstrate that the venom of an elapid, the black necked spitting cobra,

Indexed as

AnimalsElapid VenomsErythrocytesHemoglobinsHemolysisNajaOxidation-ReductionSheepElapid VenomsHemoglobinshaemoglobinmethaemoglobinneglected tropical diseaseSnakebitespitting cobravenom

Identifiers

PMID30558289
PMCPMC6316634
OpenAlexW2903971858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.