ReviewAntibiotics (Basel, Switzerland)2018
Biocidal Agents Used for Disinfection Can Enhance Antibiotic Resistance in Gram-Negative Species.
Review in Antibiotics (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
124 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chlorhexidine solutions are more effective than povidone-iodine solutions as skin disinfectants for the prevention of intravascular catheter-related infections: A meta-analysis.Scientific reports · 2025Pooled it
- Assessment of Candida attributes under in vitro repeated exposure to hydrogen peroxide.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Article
- Biofilm-driven LPS remodeling and colanic acid overproduction mediate biocide adaptation and antibiotic cross-resistance in E. coli.npj antimicrobials and resistance · 2026Article
- Whole-Genome Sequencing and Genomic Characterization of a Multi-Drug Resistant Phenotype ofMicroorganisms · 2026Article
- Beyond Antibiotics: The Expanding Role of Non-Antibiotic Therapies in Veterinary Ophthalmology.Veterinary sciences · 2026Review
- Efficacy of a novel bacteriophage in controlling Escherichia coli associated with swine farm environments and its potential for biofilm disruption.Scientific reports · 2026Article
- Application of Peracetic Acid in Poultry Processing: Effects of Treatment Dynamics and Emerging Risk of Resistance Development in Salmonella spp.Comprehensive reviews in food science and food safety · 2026Review
- Antimicrobial Peptides as Next-Generation Disinfectants: Tackling Biocide and Antimicrobial Resistance in Hospital Hygiene - A Narrative Review.Probiotics and antimicrobial proteins · 2026Review
- Chicken cecal microbial functional gene content and resistome differ by age and barn disinfection practice.Microbiology spectrum · 2026Article
- Disinfectant-induced bacterial resistance and antibiotic cross-resistance-mechanisms and clinical relevance.Clinical and experimental medicine · 2025Review
- Irrigation Solutions in Wound Care and Breast Surgery: Evidence-Based Applications, Regulatory Considerations, and Future Directions.Journal of clinical medicine · 2025Article
- Review
- Assessing the performance of a disposable electrochemical biofilm test kit on monitoring drainage sludge biofilm corrosion and its biocide treatment.Bioprocess and biosystems engineering · 2025Article
- Octenidine effectively reduces Candida auris colonisation on human skin.Scientific reports · 2025Article
- Prevalence of mutations associated with tolerance to chlorhexidine and other cationic biocides amongMicrobiology (Reading, England) · 2025Article
- Effect of cationic antiseptics on the vectorial electron and proton transfer in chromatophores of photosynthetic bacteria.Photosynthesis research · 2025Article
- Probiotic-Based Approaches for Sustainable Control of Infectious Risk in Mass Transport: Current Data and Future Perspectives.Microbial biotechnology · 2025Review
- A review of advancements in antiseptics for wound care in diabetic and non-diabetic patients.Journal of diabetes and metabolic disorders · 2025Review
- Profiling the resistome and virulome of Bacillus strains used for probiotic-based sanitation: a multicenter WGS analysis.BMC genomics · 2025Article
64 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biocidal agents used for disinfection are usually not suspected to enhance cross-resistance to antibiotics. The aim of this review was therefore to evaluate the effect of 13 biocidal agents at sublethal concentrations on antibiotic resistance in Gram-negative species. A medline search was performed for each biocidal agent on antibiotic tolerance, antibiotic resistance, horizontal gene transfer, and efflux pump. In cells adapted to benzalkonium chloride a new resistance was most frequently found to ampicillin (eight species), cefotaxime (six species), and sulfamethoxazole (three species), some of them with relevance for healthcare-associated infections such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.