Evidence map›Paper›PMID 30558158›Full record

ArticleMolecules (Basel, Switzerland)2018

Enhancement of Berberine Hypoglycemic Activity by Oligomeric Proanthocyanidins.

Haoyue Zhang, Xueping Wang, Ting Wang, Kaixian Chen, Heyao Wang, Qi Jia, Yiming Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. A Review ofMolecules (Basel, Switzerland) · 2023
    Review
  5. Effect of Oregon grape root extracts on P-glycoprotein mediated transport inJournal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2023
    Article
  6. Article
  7. Article
  8. Pharmacokinetics and Pharmacological Activities of Berberine in Diabetes Mellitus Treatment.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Haoyue ZhangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China. 13817075605@163.com.ORCID 0000-0003-1712-3421
Xueping WangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China. xueping723@163.com.
Ting WangShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. zhenwojingcaihaha@126.com.
Kaixian ChenSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China. 0000008001@shutcm.edu.cn.
Heyao WangShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. hywang@simm.ac.cn.
Qi JiaSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China. q_jia@126.com.
Yiming LiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China. ymli@shutcm.edu.cn.
Shanghai University of Traditional Chinese Medicine · CNChinese Academy of Sciences · CN

Funding

Excellent Academic Leaders Program of Shanghai 16XD1403500Natural Science Foundation of Shanghai 15ZR1441200Natural Science Foundation of Shanghai 15ZR1441500"Shanghai E-Research Institute of Bioactive Constituent in TCM" Plan /
6 · The paper itself

Abstract

This study investigated the possible enhancement of berberine's (BB) hypoglycemic activity by oligomeric proanthocyanidins (OPCs) and its underlying mechanism. The hypoglycemic activity of the studied compounds was evaluated in diabetic

Indexed as

AnimalsATP Binding Cassette Transporter, Subfamily B, Member 1BerberineBiological TransportCaco-2 CellsChromatography, LiquidHumansHypoglycemic AgentsMaleMiceMice, Inbred C57BLProanthocyanidinsRhodaminesTandem Mass SpectrometryATP Binding Cassette Transporter, Subfamily B, Member 1BerberineHypoglycemic AgentsProanthocyanidinsRhodaminesberberinehypoglycemic effectoligomeric proanthocyanidinsP-glycoproteinpharmacokinetics

Identifiers

PMID30558158
PMCPMC6321252
OpenAlexW2903593032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.