Evidence map›Paper›PMID 30558142›Full record

ReviewInternational journal of molecular sciences2018

Role of Cytokinins in Senescence, Antioxidant Defence and Photosynthesis.

Martin Hönig, Lucie Plíhalová, Alexandra Husičková, Jaroslav Nisler, Karel Doležal

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Abiotic Stress in Crop Production.International journal of molecular sciences · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. The Influence of Humic Substances and Auxin-Producing Bacteria onInternational journal of molecular sciences · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
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  13. Article
  14. Impact of theCells · 2025
    Article
  15. Article
  16. Trans-Zeatin EnhancesMicroorganisms · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martin HönigDepartment of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic. martin.honig@upol.cz.
Lucie PlíhalováDepartment of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic. lucie.plihalova@upol.cz.ORCID 0000-0001-8177-6844
Alexandra HusičkováDepartment of Biophysics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic. alexandra.husickova@upol.cz.ORCID 0000-0002-9753-8119
Jaroslav NislerDepartment of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic. jaroslav.nisler@gmail.com.
Karel DoležalDepartment of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic. karel.dolezal@upol.cz.

Funding

ERDF CZ.02.1.01/0.0/0.0/17_048/0007323
6 · The paper itself

Abstract

Cytokinins modulate a number of important developmental processes, including the last phase of leaf development, known as senescence, which is associated with chlorophyll breakdown, photosynthetic apparatus disintegration and oxidative damage. There is ample evidence that cytokinins can slow down all these senescence-accompanying changes. Here, we review relationships between the various mechanisms of action of these regulatory molecules. We highlight their connection to photosynthesis, the pivotal process that generates assimilates, however may also lead to oxidative damage. Thus, we also focus on cytokinin induction of protective responses against oxidative damage. Activation of antioxidative enzymes in senescing tissues is described as well as changes in the levels of naturally occurring antioxidative compounds, such as phenolic acids and flavonoids, in plant explants. The main goal of this review is to show how the biological activities of cytokinins may be related to their chemical structure. New links between molecular aspects of natural cytokinins and their synthetic derivatives with antisenescent properties are described. Structural motifs in cytokinin molecules that may explain why these molecules play such a significant regulatory role are outlined.

Indexed as

AntioxidantsCytokininsFlavonoidsMolecular StructurePhotosynthesisPlant DevelopmentPlant LeavesPlantsStructure-Activity RelationshipAntioxidantsCytokininsFlavonoidsantioxidantantioxidant enzymesantisenescentcytokininderivativegenesphotosynthesisplant defencestructure and activity relationship

Identifiers

PMID30558142
PMCPMC6321018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.