Evidence map›Paper›PMID 30558107›Full record

ReviewBiomolecules2018

Quantification of Lipids: Model, Reality, and Compromise.

Spiro Khoury, Cécile Canlet, Marlène Z Lacroix, Olivier Berdeaux, Juliette Jouhet, Justine Bertrand-Michel

Abstract readReview
In one paragraph

Review in Biomolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Review
  3. Lipidome Complexity in Physiological and Pathological Skin Pigmentation.International journal of molecular sciences · 2025
    Review
  4. Evaluation of normalization strategies for mass spectrometry-based multi-omics datasets.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  5. Sterols in plant biologyCell surface (Amsterdam, Netherlands) · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Opto-Lipidomics of Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Choice of buffer in mobile phase can substantially alter peak areas in quantification of lipids by HPLC-ELSD.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Spiro KhouryCentre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRA, Université Bourgogne Franche-Comté, 9E Boulevard Jeanne d'Arc, F-21000 Dijon, France. spiro.khoury@inra.fr.ORCID 0000-0003-0365-7406
Cécile CanletToxalim, Research Centre in Food Toxicology, Université de Toulouse, INRA, ENVT, INP-Purpan, UPS, F-31027 Toulouse, France. cecile.canlet@inra.fr.
Marlène Z LacroixINTHERES, Université de Toulouse, INRA, ENVT, 31432 Toulouse, France. m.lacroix@envt.fr.
Olivier BerdeauxCentre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRA, Université Bourgogne Franche-Comté, 9E Boulevard Jeanne d'Arc, F-21000 Dijon, France. olivier.berdeaux@dijon.inra.fr.
Juliette JouhetFrench LipidomYstes Network, 31000 Toulouse, France. juliette.jouhet@cea.fr.
Justine Bertrand-MichelFrench LipidomYstes Network, 31000 Toulouse, France. justine.bertrand-michel@inserm.fr.ORCID 0000-0001-9815-1517

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipids are key molecules in various biological processes, thus their quantification is a crucial point in a lot of studies and should be taken into account in lipidomics development. This family is complex and presents a very large diversity of structures, so analyzing and quantifying all this diversity is a real challenge. In this review, the different techniques to analyze lipids will be presented: from nuclear magnetic resonance (NMR) to mass spectrometry (with and without chromatography) including universal detectors. First of all, the state of the art of quantification, with the definitions of terms and protocol standardization, will be presented with quantitative lipidomics in mind, and then technical considerations and limitations of analytical chemistry's tools, such as NMR, mass spectrometry and universal detectors, will be discussed, particularly in terms of absolute quantification.

Indexed as

ChromatographyMagnetic Resonance SpectroscopyMass SpectrometryHumansLipid MetabolismLipidsLipidslipidomicmass spectrometrynuclear magnetic resonancequantificationuniversal detector

Identifiers

PMID30558107
PMCPMC6316828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.