Evidence map›Paper›PMID 30557981›Full record

ReviewMedicine2018

An ectopic adrenocortical adenoma in renal hilum presenting with Cushing's syndrome: A case report and literature review.

Difei Lu, Nan Yu, Xiaowei Ma, Junqing Zhang, Xiaohui Guo

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Difei LuDepartment of Endocrinology, Peking University First Hospital, China.
Nan Yu
Xiaowei Ma
Junqing Zhang
Xiaohui Guo
Creative Commons · USPeking University First Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleEctopic adrenal tissue is the adrenal rests along the path from gonads to adrenal glands during embryogenesis. Ectopic adrenocortical adenoma is a rare disease represented with over-production of cortisol by the ectopic adrenocortical tissue. PATIENT CONCERNS: An 18-year-old Chinese female patient was presented with weight-gain for 6 months. She had elevated plasma cortisol and a solitary mass was revealed using computed tomography scan in the left renal hilum. DIAGNOSIS: The tumor was removed and the immunohistochemical profile indicated an ectopic adrenocortical adenoma.

interventionsAfter the tumor was removed, the patient was under glucocorticoid replacement therapy in 6-month. OUTCOMES: During 6-month of follow-up, the patient showed no signs of tumor recurrence. LESSONS: Ectopic adrenocortical adenoma is difficult to diagnose due to its low incidence, and the ectopic rests in renal hilum could be misdiagnosed as renal cell carcinoma. This case reminds clinicians to be aware of ectopic site in the diagnosis of adrenocorticotropic hormone (ACTH) independent Cushing's syndrome. Immunohistochemical stain may assist in evaluating the origin of the ectopic rests. A certain rate of local recurrence indicated the need of long-term follow-up.

Indexed as

AdolescentAdrenocortical AdenomaChoristomaCushing SyndromeFemaleHumansMART-1 AntigenSynaptophysinTomography, X-Ray ComputedVimentinWeight GainMART-1 AntigenMLANA protein, humanSynaptophysinSYP protein, humanVimentin

Identifiers

PMID30557981
PMCPMC6319990
OpenAlexW2913534981

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.