Evidence map›Paper›PMID 30557554›Full record

ArticleBiochemical pharmacology2019

Inositol hexakisphosphate increases the size of platelet aggregates.

Maria A Brehm, Ulrike Klemm, Christoph Rehbach, Nina Erdmann, Katra Kolšek, Hongying Lin, Camilo Aponte-Santamaría, Frauke Gräter, Bernhard H Rauch, Andrew M Riley and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Biochemical pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. The Relevance of Phytate for the Treatment of Chronic Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2024
    Review
  2. Multiple inositol phosphate species enhance stability of active mTOR.bioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Signalling Properties of Inositol Polyphosphates.Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Maria A BrehmDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ulrike KlemmDepartment of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christoph RehbachDepartment of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.
Nina ErdmannDepartment of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.
Katra KolšekMolecular Biomechanics Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.
Hongying LinDepartment of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.
Camilo Aponte-SantamaríaMolecular Biomechanics Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.
Frauke GräterMolecular Biomechanics Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.
Bernhard H RauchInstitute of Pharmacology, University Medicine Greifswald, Ernst-Moritz-Arndt University, Felix-Hausdorff-Str. 3, 17487 Greifswald, Germany.
Andrew M RileyMedicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom.
Georg W MayrDepartment of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.
Barry V L PotterMedicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom.
Sabine WindhorstDepartment of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany. Electronic address: s.windhorst@uke.de.
Universität Hamburg · DEHeidelberg Institute for Theoretical Studies · DEUniversity of Oxford · GB

Funding

Wellcome TrustWellcome Trust 101010
6 · The paper itself

Abstract

The inositol phosphates, InsP

Indexed as

Blood PlateletsFibrinogenHumansPhytic AcidPlatelet AggregationProtein Structure, SecondaryFibrinogenPhytic AcidAggregationFibrinogenInositol hexakisphosphatePlatelets

Identifiers

PMID30557554
PMCPMC6372069
OpenAlexW2904182847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.