Evidence map›Paper›PMID 30557453›Full record

ArticleJournal of veterinary internal medicine2019

Detection of naturally occurring alloantibody by an in-clinic antiglobulin-enhanced and standard crossmatch gel column test in non-transfused domestic shorthair cats.

Isabelle Goy-Thollot, Alexandra Nectoux, Maryline Guidetti, Benjamin Chaprier, Sarah Bourgeois, Catherine Boisvineau, Anthony Barthélemy, Céline Pouzot-Nevoret, Urs Giger

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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  3. Evaluation of post-transfusion RBC alloimmunization in dogs using a gel-column crossmatch with and without anti-canine globulin enhancement.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
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  15. Multicenter Retrospective Study of Xenotransfusion of Canine Plasma Products to Cats: 14 Cases (2022-2024).Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Isabelle Goy-ThollotSIAMU (ICU), Université de Lyon, VetAgro Sup, APCSe, Marcy l'Etoile, France.ORCID https://orcid.org/0000-0003-0531-7827
Alexandra NectouxSIAMU (ICU), Université de Lyon, VetAgro Sup, APCSe, Marcy l'Etoile, France.
Maryline GuidettiDianov Laboratories, Limonest, France.
Benjamin ChaprierDianov Laboratories, Limonest, France.
Sarah BourgeoisDianov Laboratories, Limonest, France.
Catherine BoisvineauSIAMU (ICU), Université de Lyon, VetAgro Sup, APCSe, Marcy l'Etoile, France.
Anthony BarthélemySIAMU (ICU), Université de Lyon, VetAgro Sup, APCSe, Marcy l'Etoile, France.ORCID https://orcid.org/0000-0001-9570-100X
Céline Pouzot-NevoretSIAMU (ICU), Université de Lyon, VetAgro Sup, APCSe, Marcy l'Etoile, France.
Urs GigerSection of Medical Genetics (PennGen), University of Pennsylvania, Philadelphia, Pennsylvania.ORCID https://orcid.org/0000-0002-4770-4107
Université Claude Bernard Lyon 1 · FRLIM College · USPenn Center for AIDS Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood typing for the A and B antigens is essential and crossmatching testing is generally recommended before transfusing blood to cats.

objectiveTo evaluate 2 crossmatch (XM) tests. ANIMALS: Forty-nine healthy domestic shorthair cats that had not received a blood transfusion.

methodsProspective study. Blood samples were typed for AB using immunochromatographic and flow cytometric techniques. A gel column (GC) and a feline antiglobulin-enhanced gel column (AGC) XM tests were used for crossmatching.

resultsThe population included 34 type A, 13 B, and 2 AB cats, with concordant results (r = 1, P < .005) by flow cytometry and immunochromatographic strip kit. The plasma from type A cats had either no or weak anti-B alloantibodies. The plasma of 12 of 13 type B cats contained strong anti-A alloantibodies. For crossmatching, plasma to RBC pairings were prepared using the GC (n = 446) and AGC (n = 630) tests. Both methods showed compatibilities in 329 and incompatibilities in 102 pairings including all A-B mismatches. Additionally 15 pairings showed agglutination by the AGC but not GC method. Fourteen incompatibilities outside the expected A-B mismatches were only revealed by AGC. CONCLUSIONS AND CLINICAL IMPORTANCE: AB typing using immunochromatographic strip is as accurate as laboratory flow cytometry. The 2 XM methods had good agreement with additional incompatibilities being recognized by the AGC XM beyond A-B incompatibilities. In clinic, feline AB typing and sensitive XM test kits are available and recommended before each transfusion, although the clinical implications of incompatible XM test results and clinical benefits of such crossmatching have not been documented.

Indexed as

ABO Blood-Group SystemAnimalsBlood Grouping and CrossmatchingBlood TransfusionCatsChromatography, AffinityCoombs TestDiagnostic Tests, RoutineFemaleMalePredictive Value of TestsProspective StudiesReagent Kits, DiagnosticABO Blood-Group SystemReagent Kits, Diagnosticblood compatibilityblood type systemsblood typingfelinehemolysistransfusion

Identifiers

PMID30557453
PMCPMC6430866
OpenAlexW2904047562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.