Evidence map›Paper›PMID 30557368›Full record

ArticlePloS one2018

Assessment of degenerative cervical myelopathy differs between specialists and may influence time to diagnosis and clinical outcomes.

Bryn Hilton, Jennifer Tempest-Mitchell, Benjamin Davies, Mark Kotter

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06528730 (A Novel Surgical Criteria for Degenerative Cervical Myelopathy in Chinese Ethnicity), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06528730 recruitingnot on this mapstarted 2023, after this paper: background citation

A Novel Surgical Criteria for Degenerative Cervical Myelopathy in Chinese Ethnicity

TypeobservationalSponsorThe University of Hong KongRan2023 to 2050Enrolled100ConditionsDegenerative Cervical Spinal StenosisArmsDCM
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

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  14. Myelopathy disability index: establishing criteria for mild, moderate and severe impairment in patients with degenerative cervical myelopathy.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bryn HiltonSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-9617-6753
Jennifer Tempest-MitchellSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-3990-140X
Benjamin DaviesAcademic Neurosurgery Unit, Department of Clinical Neurosurgery, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-0591-5069
Mark KotterAcademic Neurosurgery Unit, Department of Clinical Neurosurgery, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionDegenerative Cervical Myelopathy [DCM] often presents with non-specific symptoms and signs. It progresses insidiously and leads to permanent neurological dysfunction. Decompressive surgery can halt disease progression, however significant delays in diagnosis result in increased disability and limit recovery. The nature of early DCM symptoms is unknown, moreover it has been suggested incomplete examination contributes to missed diagnosis. This study examines how DCM is currently assessed, if assessment differs between stages of healthcare, and whether this influences patient management. STUDY

designRetrospective cohort study.

methodsCervical MRI scans (N = 1123) at a tertiary neurosciences center, over a single year, were screened for patients with DCM (N = 43). Signs, symptoms, and disease severity of DCM were extracted from patient records. Patients were considered at 3 phases of clinical assessment: primary care, secondary care, and surgical assessment.

resultsUpper limb paraesthesia and urinary dysfunction were consistently the most and least prevalent symptoms respectively. Differences between assessing clinicians were present in the reporting of: limb pain (p<0.005), objective limb weakness (p = 0.01), hyperreflexia (p<0.005), Hoffmann reflex (p<0.005), extensor plantar reflex (p = 0.007), and lower limb spasticity (p<0.005). Pathological reflexes were least frequently assessed by primary care doctors.

conclusionDCM assessment varies significantly between assessors. Reporting of key features of DCM is especially low in primary care. Incomplete assessment may hinder early diagnosis and referral to spinal surgery.

Indexed as

AdultAgedAged, 80 and overCervical VertebraeCohort StudiesDelayed DiagnosisFemaleHumansInfant, NewbornMagnetic Resonance ImagingMaleMiddle AgedNeurodegenerative DiseasesNeurosurgerySpecializationSpinal Cord Compression

Identifiers

PMID30557368
PMCPMC6296508
OpenAlexW2903587933

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.