ReviewCurrent opinion in psychiatry2019
Understanding and predicting the longitudinal course of dementia.
Review in Current opinion in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Reflections on dynamic prediction of Alzheimer's disease: advancements in modeling longitudinal outcomes and time-to-event data.BMC medical research methodology · 2025Pooled it
- Systematic review of prognostic factors for poor outcome in people living with dementia that can be determined from primary care medical records.BMC geriatrics · 2024Pooled it
- Defining end of life in dementia: A systematic review.Palliative medicine · 2021Pooled it
- Orthostatic Blood Pressure Recovery Is Associated With the Rate of Cognitive Decline and Mortality in Clinical Alzheimer's Disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- Prognostic factors for functional decline in community-dwelling older adults with dementia: a systematic review and meta-analysis.European geriatric medicine · 2026Review
- Documented follow-up to memory concerns reported at the Medicare Annual Wellness Visit.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Coevolution of Cognitive and Health Trajectories Among US Older Adults With Cognitive Impairment.Journal of the American Medical Directors Association · 2026Article
- Reimagining the 'Lost' narratives of advanced dementia through literature and critical fabulation.Medical humanities · 2026Article
- "We can do this. That I learned.": A nonrandomized open pilot of Resilient Together for Dementia, a post-diagnosis dyadic intervention.BMC geriatrics · 2026Article
- Neuropsychiatric symptoms and gait/balance are predictors of functional trajectories in dementias.Dementia & neuropsychologia · 2026Article
- Latent classes and progression of Mini-Mental State Examination scores in young-onset dementia: Data from the Swedish Dementia Register.Journal of Alzheimer's disease : JAD · 2025Article
- Care Recipients' Cognitive Trajectories and Caregivers' Depressive Symptoms: The Mediating Role of Caregiving Burden.The Gerontologist · 2025Article
- Health literacy in relation to web-based measurement of cognitive function in the home: UK Women's Cohort Study.BMJ open · 2025Article
- A Live Video Resiliency Dyadic Intervention for Persons With Dementia and Their Care-Partners Early After Diagnosis: Protocol for Open Pilot of Resilient Together for Dementia.JMIR research protocols · 2025Article
- Mortality and Function After Widowhood Among Older Adults With Dementia, Cancer, or Organ Failure.JAMA network open · 2024Article
- Educational disparities in brain health and dementia across Latin America and the United States.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Cerebrospinal fluid neutral lipids predict progression from mild cognitive impairment to Alzheimer's disease.GeroScience · 2024Article
- Heart Rate Variability and Cognition: A Narrative Systematic Review of Longitudinal Studies.Journal of clinical medicine · 2024Review
- Temporal atrophy together with verbal encoding impairment is highly predictive for cognitive decline in typical Alzheimer's dementia - a retrospective follow-up study.Frontiers in psychiatry · 2024Article
- Examining heterogeneity in dementia using data-driven unsupervised clustering of cognitive profiles.PloS one · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo date, most research in dementia has focused either on the identification of dementia risk prediction or on understanding changes and predictors experienced by individuals before diagnosis. Despite little is known about how individuals change after dementia diagnosis, there is agreement that changes occur over different time scales and are multidomain. In this study, we present an overview of the literature regarding the longitudinal course of dementia. RECENT
findingsOur review suggests the evidence is scarce and findings reported are often inconsistent. We identified large heterogeneity in dementia trajectories, risk factors considered and modelling approaches employed. The heterogeneity of dementia trajectories also varies across outcomes and domains investigated. SUMMARY: It became clear that dementia progresses very differently, both between and within individuals. This implies an average trajectory is not informative to individual persons and this needs to be taken into account when communicating prognosis in clinical care. As persons with dementia change in many more ways during their patient journey, heterogeneous disease progressions are the result of disease and patient characteristics. Prognostic models would benefit from including variables across a number of domains. International coordination of replication and standardization of the research approach is recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.