Evidence map›Paper›PMID 30557230›Full record

Trial reportJournal of neurosurgical anesthesiology2019

Home-based Cognitive Prehabilitation in Older Surgical Patients: A Feasibility Study.

Phillip E Vlisides, Abhijit R Das, Allie M Thompson, Bryan Kunkler, Mackenzie Zierau, Michael J Cantley, Amy M McKinney, Bruno Giordani

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neurosurgical anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 12 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 12 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Phillip E VlisidesDepartment of Anesthesiology.
Abhijit R DasNortheast Ohio Medical University, Rootstown, OH.
Allie M ThompsonDepartment of Anesthesiology.
Bryan KunklerDepartment of Anesthesiology.
Mackenzie ZierauDepartment of Anesthesiology.
Michael J CantleyDepartment of Anesthesiology.
Amy M McKinneyDepartment of Anesthesiology.
Bruno GiordaniDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI.
Northeast Ohio Medical University · USUniversity of Michigan–Ann Arbor · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Neurocognitive Recovery following Surgery and General AnesthesiaK23GM126317 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VLISIDES, PHILLIP ELEAS · 2018 to 2021
$764k
NCATS NIH HHS UL1 TR002240NIGMS NIH HHS K23 GM126317
6 · The paper itself

Abstract

backgroundCognitive training is beneficial in various clinical settings, although its perioperative feasibility and impact remain unknown. The objective of this pilot study was to determine the feasibility of home-based cognitive prehabilitation before major surgery in older adults. MATERIALS AND

methodsSixty-one patients were enrolled, randomized, and allocated to either a home-based preoperative cognitive training regimen or no training before surgery. Outcomes included postoperative delirium incidence (primary outcome; assessed with the 3D-Confusion Assessment Method), perioperative cognitive function based on NIH Toolbox measures, hospital length of stay, and physical therapy session participation. Reasons for declining enrollment were reported, as were reasons for opting out of the training program.

resultsPostoperative delirium incidence was 6 of 23 (26%) in the prehabilitation group compared with 5 of 29 (17%) in the control group (P=0.507). There were no significant differences between groups in NIH Toolbox cognitive function scoring, hospital length of stay, or physical therapy participation rates. Study feasibility data were also collected and reported. The most common reasons for declining enrollment were lack of computer access (n=19), time commitment (n=9), and feeling overwhelmed (n=9). In the training group, only 5 of 29 (17%) included patients were able to complete the prescribed 7 days of training, and 14 of 29 (48%) opted out of training once home. Most common reasons were feeling overwhelmed (n=4) and computer difficulties (n=3).

conclusionsShort-term, home-based cognitive training before surgery is unlikely to be feasible for many older patients. Barriers to training include feeling overwhelmed, technical issues with training, and preoperative time commitment.

Indexed as

Home Care ServicesAgedCognition DisordersDeliriumFeasibility StudiesFemaleHumansIncidenceLength of StayMaleMiddle AgedNeuropsychological TestsPatient DropoutsPhysical Therapy ModalitiesPilot ProjectsPostoperative Complications

Identifiers

PMID30557230
PMCPMC6652226
OpenAlexW2905883618

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.