ArticleThe Angle orthodontist2019
Incidence of white spot lesions among patients treated with clear aligners and traditional braces.
Article in The Angle orthodontist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06616207 (Efficacy and Safety of Topical 10% Povidone-Iodine in Preventing White Spots During Orthodontic Treatment), which is not on this map. Cited by 46 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Topical 10% Povidone-Iodine in Preventing White Spots During Orthodontic Treatment
Who cites it
46 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Adverse effects of removable orthodontic aligners: A systematic review with single-arm meta-analysis.PloS one · 2026Pooled it
- Comparative evaluation of physical and mechanical properties of clear aligners - a systematic review.Evidence-based dentistry · 2024Pooled it
- White spot lesions, plaque accumulation and salivary caries-associated bacteria in clear aligners compared to fixed orthodontic treatment. A systematic review and meta- analysis.BMC oral health · 2023Pooled it
- Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the Application of Infiltrative Resins: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Impact of Aligners and Fixed Appliances on Oral Health during Orthodontic Treatment: A Systematic Review and Meta-Analysis.Oral health & preventive dentistry · 2021Pooled it
- Prevention of non-cavitated lesions with fluoride and xylitol varnishes during orthodontic treatment: a randomized clinical trial.Clinical oral investigations · 2021Trial
- Evaluation of Antibacterial Effect and Mechanical Properties of Thermoformed Clear Aligners Coated with Chitosan and Cellulose Nanocrystals.Journal of dentistry (Shiraz, Iran) · 2026Article
- Functionalization of a Shape-Memory 3D-Printed Clear Aligner Resin with Silanized Chitosan Nanoparticles: Antibacterial, Optical, Polymerization, and Mechanical Evaluation.Journal of functional biomaterials · 2026Article
- Incidence and distribution of white spot lesions after clear aligner versus fixed appliance therapy : A retrospective digital photograph and intraoral scan analysis.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026Article
- Construction of caries risk assessment scale and oral microecology analysis of adolescents with fixed orthodontic treatment.BMC oral health · 2026Article
- Comparison of conventional and self-adhesive orthodontic bonding systems in white spot lesion formation: an in vitro confocal Raman microscopy analysis.The Angle orthodontist · 2026Article
- Review
- Evaluating the Impact of Clear Dental Aligners on Dental and Periodontal Conditions, Oral Microbial Patterns, and the Immune System.Advances in experimental medicine and biology · 2026Review
- How AI-Driven Root and Bone Predictions Can Assist Clear Aligner Treatment Planning.Orthodontics & craniofacial research · 2025Review
- Duration-Dependent Caries Risk During Clear Aligner Therapy: A Retrospective Analysis.Biomimetics (Basel, Switzerland) · 2025Article
- Assessment of internet data on orthodontic treatment and oral hygiene in the Marmara region using Google Trends:a methodological study.European oral research · 2025Article
- Effectiveness and Clinical Indications of 2 × 4 Fixed Orthodontic Therapy in Regard to Mixed Dentition: A Systematic Review.Children (Basel, Switzerland) · 2025Review
- Effects of different corticotomy approaches on anterior retraction with clear aligners: a finite element study.BMC oral health · 2025Article
- Comparative Study of Proximal Caries Formation and Decay, Missing, Filled Teeth Scores in Clear Aligners and Fixed Orthodontic Treatments.Turkish journal of orthodontics · 2025Article
- Expert consensus on the prevention and treatment of enamel demineralization in orthodontic treatment.International journal of oral science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the incidence of white spot lesions (WSLs) among patients treated with aligners and those treated with traditional braces. MATERIALS AND
methodsA group of 244 aligner patients (30.4 ± 14 years) was compared to a group of 206 patients (29.2 ± 11.5 years) treated with traditional fixed braces. Consecutive cases in the late mixed or permanent dentitions who had high-quality pre- and posttreatment digital photographs available were included in the study. Each set of photographs was independently evaluated by two investigators to determine pretreatment oral hygiene (OH), fluorosis, and WSLs, as well as changes in OH and WSLs during treatment.
resultsApproximately 1.2% of the aligner patients developed WSLs, compared to 26% of the traditionally treated patients. The numbers of WSLs that developed were also significantly (
conclusionsPatients treated with aligners have less risk of developing WSLs than do patients treated with traditional braces, which could be partially due to shorter treatment duration, or better pretreatment OH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.