Evidence map›Paper›PMID 30556449›Full record

ReviewThe Journal of international medical research2019

Intravitreal fluocinolone acetonide implant (ILUVIEN®) for diabetic macular oedema: a literature review.

Horace Massa, Anindyt M Nagar, Athanasios Vergados, Panagiotis Dadoukis, Sudeshna Patra, Georgios D Panos

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Incidence and treatment approach of intraocular pressure elevation after various types of local steroids for retinal diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  5. Review
  6. Intravitreal Fluocinolone Acetonide Implant (ILUVIENDrug design, development and therapy · 2023
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Horace Massa1 Department of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-5025-3856
Anindyt M Nagar2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
Athanasios Vergados2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
Panagiotis Dadoukis2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
Sudeshna Patra2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
Georgios D Panos2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.ORCID https://orcid.org/0000-0001-8399-7456
Barts Health NHS Trust · GBUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy and may lead to severe visual loss. In this review, we describe the pathophysiology of DMO and review current therapeutic options such as macular laser photocoagulation, anti-vascular endothelial growth factor agents, and steroid implants with a focus on the new fluocinolone acetonide implant, ILUVIEN®. The results of the Fluocinolone Acetonide in Diabetic Macular Edema (FAME) studies are also presented together with the results of real-world studies to support the clinical use of ILUVIEN® in achieving efficient resolution of DMO and improving vision and macular anatomy in this challenging group of patients.

Indexed as

Angiogenesis InhibitorsAnti-Inflammatory AgentsDiabetic RetinopathyDrug ImplantsFluocinolone AcetonideHumansIntravitreal InjectionsLight CoagulationLow-Level Light TherapyMacular EdemaPatient SafetyTreatment OutcomeVascular Endothelial Growth Factor AAngiogenesis InhibitorsAnti-Inflammatory AgentsDrug ImplantsFluocinolone AcetonideVascular Endothelial Growth Factor AVEGFA protein, humananti-VEGF agentsdiabetesDiabetic macular oedemadiabetic retinopathyfluocinolone acetonideILUVIENintravitreal injectionssteroid implant

Identifiers

PMID30556449
PMCPMC6384476
OpenAlexW2904517294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.