Evidence map›Paper›PMID 30556348›Full record

ReviewAdvanced healthcare materials2019

Tissue Engineering for the Temporomandibular Joint.

Timothy M Acri, Kyungsup Shin, Dongrim Seol, Noah Z Laird, Ino Song, Sean M Geary, Jaidev L Chakka, James A Martin, Aliasger K Salem

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Artificial Intelligence in Dentistry: A Descriptive Review.Bioengineering (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Heliyon · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Timothy M AcriDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA.
Kyungsup ShinDepartment of Orthodontics, College of Dentistry and Dental Clinics, University of Iowa, Iowa City, Iowa, 52242, USA.
Dongrim SeolDepartment of Orthopedics and Rehabilitation, Carver College of Medicine, University of Iowa, Iowa City, Iowa, 52242, USA.
Noah Z LairdDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA.
Ino SongDepartment of Orthopedics and Rehabilitation, Carver College of Medicine, University of Iowa, Iowa City, Iowa, 52242, USA.
Sean M GearyDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA.
Jaidev L ChakkaDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA.
James A MartinDepartment of Orthopedics and Rehabilitation, Carver College of Medicine, University of Iowa, Iowa City, Iowa, 52242, USA.
Aliasger K SalemDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA.ORCID 0000-0002-1923-6633

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
A Novel RNA Based Biomaterial for Bone RegenerationR21DE024206 · NIDCR · UNIVERSITY OF IOWA · PI ELANGOVAN, SATHEESH · 2015 to 2016
$406k
American Association of Orthodontists FoundationLyle and Sharon Bighley ProfessorshipNCI NIH HHS P30 CA086862NIDCR NIH HHS R21 DE024206NIEHS NIH HHS P30 ES005605NIH HHS 1R21DE024206-01A1
6 · The paper itself

Abstract

Tissue engineering potentially offers new treatments for disorders of the temporomandibular joint which frequently afflict patients. Damage or disease in this area adversely affects masticatory function and speaking, reducing patients' quality of life. Effective treatment options for patients suffering from severe temporomandibular joint disorders are in high demand because surgical options are restricted to removal of damaged tissue or complete replacement of the joint with prosthetics. Tissue engineering approaches for the temporomandibular joint are a promising alternative to the limited clinical treatment options. However, tissue engineering is still a developing field and only in its formative years for the temporomandibular joint. This review outlines the anatomical and physiological characteristics of the temporomandibular joint, clinical management of temporomandibular joint disorder, and current perspectives in the tissue engineering approach for the temporomandibular joint disorder. The tissue engineering perspectives have been categorized according to the primary structures of the temporomandibular joint: the disc, the mandibular condyle, and the glenoid fossa. In each section, contemporary approaches in cellularization, growth factor selection, and scaffold fabrication strategies are reviewed in detail along with their achievements and challenges.

Indexed as

Temporomandibular JointAnimalsGlenoid CavityHumansIntercellular Signaling Peptides and ProteinsMandibular CondyleStem CellsTemporomandibular Joint DiscTemporomandibular Joint DisordersTissue EngineeringTissue ScaffoldsIntercellular Signaling Peptides and Proteinsanimal studiescellsgrowth factorsscaffoldstemporomandibular jointtissue engineering

Identifiers

PMID30556348
PMCPMC7075314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.