Evidence map›Paper›PMID 30556259›Full record

ArticleJournal of applied clinical medical physics2019

Automatic measurement of air gap for proton therapy using orthogonal x-ray imaging with radiopaque wires.

Pavitra Ramesh, Wei Song, Hongbin Cao, Yanqun Zhao, Rahul Parikh, Joseph Weiner, Xiao Wang, Ke Nie, Ning Yue, Yin Zhang

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Pavitra RameshDepartment of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson University Hospital, Rutgers-The State University of New Jersey, New Brunswick, NJ, USA.
Wei SongDepartment of Radiation Oncology, Jiangsu Province Hospital of TCM, Nanjing, Jiangsu, China.
Hongbin CaoDepartment of Radiation Oncology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Yanqun ZhaoSichuan Cancer Center, School of Medicine, Sichuan Cancer Hospital & Institute, University of Electronic Science and Technology of China, Chengdu, China.
Rahul ParikhDepartment of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson University Hospital, Rutgers-The State University of New Jersey, New Brunswick, NJ, USA.
Joseph WeinerDepartment of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson University Hospital, Rutgers-The State University of New Jersey, New Brunswick, NJ, USA.
Xiao WangDepartment of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson University Hospital, Rutgers-The State University of New Jersey, New Brunswick, NJ, USA.
Ke NieDepartment of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson University Hospital, Rutgers-The State University of New Jersey, New Brunswick, NJ, USA.
Ning YueDepartment of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson University Hospital, Rutgers-The State University of New Jersey, New Brunswick, NJ, USA.
Yin ZhangDepartment of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson University Hospital, Rutgers-The State University of New Jersey, New Brunswick, NJ, USA.
Robert Wood Johnson University Hospital · USRutgers, The State University of New Jersey · USJiangsu Province Hospital · CNRenji Hospital · CNSichuan Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe main objective of this study was to develop a technique to accurately determine the air gap between the end of the proton beam compensator and the body of the patient in proton radiotherapy.

methodsOrthogonal x-ray image-based automatic coordinate reconstruction was used to determine the air gap between the patient body surface contour and the end of beam nozzle in proton radiotherapy. To be able to clearly identify the patient body surface contour on the orthogonal images, a radiopaque wire was placed on the skin surface of the patient as a surrogate. In order to validate this method, a Rando

resultsOn the phantom study, the air gap values derived with the automatic reconstruction method were found to be within 1.1 mm difference from the planned values for proton beams with air gaps of 85.0, 100.0, 150.0, 180.0, and 200.0 mm. The reconstruction technique determined air gaps for a patient in two clinical treatment sessions were 38.4 and 41.8 mm, respectively, for a 40 mm planned air gap, and confirmed by manual measurements. There was strong agreement between the calculated values and the automatically measured values, and between the automatically and manually measured values.

conclusionsAn image-based automatic method has been developed to conveniently determine the air gap of a proton beam, directly using the orthogonal images for patient positioning without adding additional imaging dose to the patient. The method provides an objective, accurate, and efficient way to confirm the target depth at treatment to ensure desired target coverage and normal tissue sparing.

Indexed as

AirPhantoms, ImagingProton TherapyArtifactsAutomationBrain NeoplasmsHeadHumansImage Processing, Computer-AssistedMonte Carlo MethodRadiotherapy DosageTomography, X-Ray Computedair gaporthogonal kV imagesproton therapy

Identifiers

PMID30556259
PMCPMC6333136
OpenAlexW2905215836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.