Evidence map›Paper›PMID 30556184›Full record

ArticleJournal of veterinary internal medicine2019

Comparison of 2 differently sized endoscopic biopsy forceps in the evaluation of intestinal disease in cats.

Enrico Bottero, Emanuele Mussi, Camillo Pieramati, Davide De Lorenzi, Serenella Silvestri, Elvio Lepri

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Enrico BotteroPoliambulatorio Argentina, Freelance Gruppo Endovet, Arma di Taggia, Italy.
Emanuele MussiClinica Veterinaria Croce Azzurra, Freelance Gruppo Endovet, Empoli, Italy.ORCID https://orcid.org/0000-0003-2260-1555
Camillo PieramatiDipartimento di Medicina Veterinaria, University of Perugia, Perugia, Italy.
Davide De LorenziOspedale Veterinario Portoni Rossi, Bologna, Italy.
Serenella SilvestriDipartimento di Medicina Veterinaria, University of Perugia, Perugia, Italy.ORCID https://orcid.org/0000-0002-2366-1210
Elvio LepriDipartimento di Medicina Veterinaria, University of Perugia, Perugia, Italy.
University of Perugia · ITAzienda Unità Sanitaria Locale 11 di Empoli · ITGruppo di Ricerca Geriatrica · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn clinical practice, histopathological diagnosis of chronic intestinal disease is challenging because of difficulty in obtaining adequate duodenal samples. At present, no studies have investigated the influence of biopsy forceps size on sample quality in cats.

objectivesDuodenal biopsy using larger biopsy forceps (2.4 mm) will provide higher quality samples. ANIMALS: Fifty client-owned cats underwent endoscopy of the upper gastrointestinal tract for evaluation of chronic gastrointestinal signs, with inflammatory bowel disease (IBD) or intestinal lymphoma as differential diagnoses.

methodsFor each cat, duodenal biopsy specimens were obtained using both small (1.8 mm) and large (2.4 mm) forceps and evaluated for adequacy, orientation, the presence of artifacts, villi morphology, the presence of inflammation, and neoplastic infiltration.

resultsThe percentage of adequate and evaluable biopsy specimens obtained using the larger forceps was significantly higher than that collected using the smaller forceps. Agreement between the forceps was variable for histological features and substantial in the case of lymphoma. However, in case of disagreement, the proper diagnosis usually was achieved only with the larger biopsy forceps. CONCLUSIONS AND CLINICAL IMPORTANCE: Use of a larger biopsy forceps allows collection of a higher percentage of adequate and evaluable biopsy specimens compared to the commonly used smaller forceps and indirectly decreases the percentage of artifacts and increases the percentage of samples with evaluable villi. The use of a larger forceps could be helpful to obtain high-quality samples and improve diagnostic accuracy.

Indexed as

AnimalsBiopsyCat DiseasesCatsDuodenumEndoscopy, GastrointestinalGastrointestinal NeoplasmsInflammatory Bowel DiseasesLymphomabiopsy forcepscatsendoscopygastrointestinal diseasesinflammatory bowel diseaselymphoma

Identifiers

PMID30556184
PMCPMC6430887
OpenAlexW2904704823

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.