Evidence map›Paper›PMID 30556096›Full record

ArticleInflammation2019

Cannabinoid CB

M C G Leite-Avalca, F T Staats, D Verona, P de Souza, M C Almeida, J E Silva-Santos, A R Zampronio

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Cannabinoids in preclinical research of sepsis: a scoping review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  3. Lactate and lactylation in macrophage polarization of sepsis.Frontiers in cellular and infection microbiology · 2025
    Review
  4. Lactate and Lactylation in Sepsis: A Comprehensive Review.Journal of inflammation research · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Targeting of G-protein coupled receptors in sepsis.Pharmacology & therapeutics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

M C G Leite-AvalcaDepartment of Pharmacology, Biological Sciences Section, Federal University of Paraná, Curitiba, Paraná, Brazil.
F T StaatsDepartment of Pharmacology, Biological Sciences Section, Federal University of Paraná, Curitiba, Paraná, Brazil.
D VeronaDepartment of Pharmacology, Biological Sciences Section, Federal University of Paraná, Curitiba, Paraná, Brazil.
P de SouzaDepartment of Pharmacology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
M C AlmeidaCenter for Natural and Human Sciences, Federal University of ABC, São Bernardo do Campo, São Paulo, Brazil.
J E Silva-SantosDepartment of Pharmacology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
A R ZampronioDepartment of Pharmacology, Biological Sciences Section, Federal University of Paraná, Curitiba, Paraná, Brazil. aleksander@ufpr.br.
Universidade Federal do Paraná · BRUniversidade Federal de Santa Catarina · BRUniversidade Federal do ABC · BR

Funding

SUBTHRESHOLD MUSCLE AFFERENT INPUT TO DORSAL HORNF06TW002012 · FIC · UNIVERSITY OF CALIFORNIA DAVIS · PI KAUFMAN, MARC PETER · 1995 to 1995
–
Conselho Nacional de Desenvolvimento Científico e Tecnológico 473194/2012-0
6 · The paper itself

Abstract

Sepsis is a life-threatening condition with high mortality rates that is caused by dysregulation of the host response to infection. We previously showed that treatment with the cannabinoid CB

Indexed as

AnimalsAortaArginine VasopressinCannabinoid Receptor AntagonistsCecumHemodynamicsMaleMultiple Organ FailureNitric OxideRatsRats, WistarRimonabantSepsisSignal TransductionSurvival RateVasoconstrictionArginine VasopressinCannabinoid Receptor AntagonistsNitric OxideRimonabantCB1 receptor antagonistorgan dysfunctionrimonabantsepsis

Identifiers

PMID30556096
OpenAlexW2904581040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.