Evidence map›Paper›PMID 30556056›Full record

ArticleConditioning medicine2018

The Role of Platelets in Ischemic Conditioning.

Juan Alpuche, Luz Quírino, José T Sánchez-Vega, Jonathan Yap, Eduardo Pérez-Campos, Hector A Cabrera-Fuentes

Abstract read
In one paragraph

Article in Conditioning medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Role of Macrophages in Cardioprotection.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan AlpucheCONACyT-Facultad de Medicina, Centro de Investigación Facultad de Medicina, UNAM-UABJO. Universidad Autónoma Benito Juárez de Oaxaca. México.
Luz QuírinoCentro de Investigación Facultad de Medicina, UNAM-UABJO. Universidad Autónoma Benito Juárez de Oaxaca.
José T Sánchez-VegaParasitology Laboratory, Department of Microbiology and Parasitology, Faculty of Medicine, Universidad Nacional Autónoma de México, México City, México.
Jonathan YapCenter for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii, Hawaii, USA.
Eduardo Pérez-CamposCentro de Investigación Facultad de Medicina, UNAM-UABJO. Universidad Autónoma Benito Juárez de Oaxaca.
Hector A Cabrera-FuentesKazan Federal University, Department of Microbiology, Kazan, Russian Federation.

Funding

Over-expression of Chitotriosidase Modulates Macrophage Function and Progression of Atherosclerosis in Hyperlipidemic, LDLr-/- MiceF31HL139082 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI YAP, JONATHAN · 2017 to 2018
$96k
NHLBI NIH HHS F31 HL139082
6 · The paper itself

Abstract

Ischemic heart disease (IHD) is one of the leading causes of death and disability worldwide. Platelets, as the main regulators of hemostasis, are major players in acute myocardial ischemia/reperfusion injury (IRI). Additionally, platelets are modified by endogenous cardioprotective strategies such as ischemic preconditioning, postconditioning, and remote ischemic conditioning. In this article, we provide an overview of the functionional role of platelets in acute myocardial IRI, and highlight their potential as targets for cardioprotection to improve health outcomes in patients with IHD.

Indexed as

cardioprotectionischemia-reperfusion injuryischemic conditioningplatelets

Identifiers

PMID30556056
PMCPMC6291202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.