ArticleACS applied bio materials2018
Fouling-Resistant Hydrogels Prepared by the Swelling-Assisted Infusion and Polymerization of Dopamine.
Article in ACS applied bio materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- Enhancing Performance of Silicone Hydrogel Contact Lenses with Hydrophilic Polyphenolic Coatings.Journal of functional biomaterials · 2024Article
- Article
- Biofouling-Resistant Ultrafiltration Membranes via Codeposition of Dopamine and Cetyltrimethylammonium Bromide with Retained Size Selectivity and Water Flux.ACS applied materials & interfaces · 2022Article
- Combinatorial Polyacrylamide Hydrogels for Preventing Biofouling on Implantable Biosensors.Advanced materials (Deerfield Beach, Fla.) · 2022Article
- Antifouling Ultrafiltration Membranes with Retained Pore Size by Controlled Deposition of Zwitterionic Polymers and Poly(ethylene glycol).Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Polymeric Composites with Embedded Nanocrystalline Cellulose for the Removal of Iron(II) from Contaminated Water.Polymers · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Biofilm-associated infections stemming from medical devices are increasingly challenging to treat due to the spread of antibiotic resistance. In this study, we present a simple strategy that significantly enhances the antifouling performance of covalently crosslinked poly(ethylene glycol) (PEG) and physically crosslinked agar hydrogels by incorporation of the fouling-resistant polymer zwitterion, poly(2-methacryloyloxyethyl phosphorylcholine) (pMPC). Dopamine polymerization was initiated during swelling of the hydrogels, which provided dopamine and pMPC an osmotic driving force into the hydrogel interior. Both PEG and agar hydrogels were synthesized over a broad range of storage moduli (1.7,1300 kPa), which remained statistically equivalent after being functionalized with pMPC and polydopamine (PDA). When challenged with fibrinogen, a model blood-clotting protein, the pMPC/PDA-functionalized PEG and agar hydrogels displayed a >90% reduction in protein adsorption compared to hydrogel controls. Further, greater than an order-of-magnitude reduction in
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Registered trials
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