Evidence map›Paper›PMID 30556011›Full record

ArticleACS omega2018

Fluorescent ZnS Quantum Dots-Phosphoethanolamine Nanoconjugates for Bioimaging Live Cells in Cancer Research.

Alexandra A P Mansur, Herman S Mansur, Sandhra M Carvalho, Zélia I P Lobato, Maria de Fátima Leite, Lorena L Mansur

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexandra A P MansurCenter of Nanoscience, Nanotechnology and Innovation-CeNanoI, Department of Preventive Veterinary Medicine, Veterinary School, and Department of Physiology and Biophysics, ICB, Federal University of Minas Gerais-UFMG, Av. Antônio Carlos, 6627 Belo Horizonte/MG, Brazil.
Herman S MansurCenter of Nanoscience, Nanotechnology and Innovation-CeNanoI, Department of Preventive Veterinary Medicine, Veterinary School, and Department of Physiology and Biophysics, ICB, Federal University of Minas Gerais-UFMG, Av. Antônio Carlos, 6627 Belo Horizonte/MG, Brazil.
Sandhra M CarvalhoCenter of Nanoscience, Nanotechnology and Innovation-CeNanoI, Department of Preventive Veterinary Medicine, Veterinary School, and Department of Physiology and Biophysics, ICB, Federal University of Minas Gerais-UFMG, Av. Antônio Carlos, 6627 Belo Horizonte/MG, Brazil.
Zélia I P LobatoCenter of Nanoscience, Nanotechnology and Innovation-CeNanoI, Department of Preventive Veterinary Medicine, Veterinary School, and Department of Physiology and Biophysics, ICB, Federal University of Minas Gerais-UFMG, Av. Antônio Carlos, 6627 Belo Horizonte/MG, Brazil.
Maria de Fátima LeiteCenter of Nanoscience, Nanotechnology and Innovation-CeNanoI, Department of Preventive Veterinary Medicine, Veterinary School, and Department of Physiology and Biophysics, ICB, Federal University of Minas Gerais-UFMG, Av. Antônio Carlos, 6627 Belo Horizonte/MG, Brazil.
Lorena L MansurCenter of Nanoscience, Nanotechnology and Innovation-CeNanoI, Department of Preventive Veterinary Medicine, Veterinary School, and Department of Physiology and Biophysics, ICB, Federal University of Minas Gerais-UFMG, Av. Antônio Carlos, 6627 Belo Horizonte/MG, Brazil.
Universidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many human diseases, including metabolic, immune, and central nervous system disorders, as well as several types of cancers, are the consequence of an important alteration in lipid-related metabolic biomolecules. Although recognized that one of the most important metabolic hallmarks of cancer cells is deregulation of lipid metabolism, the multiple complex signaling pathways are poorly understood yet. Thus, in this research, novel nanoconjugates made of ZnS quantum dots (QDs) were directly synthesized in aqueous media using phosphoethanolamine (PEA) as the capping ligand, which is an important biomolecule naturally present in cells for de novo biosynthesis of fatty acids and phospholipids involved in the cell structure (e.g., membrane), differentiation, and cancer growth. These QD-PEA bio-nanoconjugates were characterized by spectroscopical and morphological techniques. The results demonstrated that fluorescent ZnS nanocrystalline QDs were produced with uniform spherical morphology and estimated sizes of 3.3 ± 0.6 nm. These nanoconjugates indicated core-shell colloidal nanostructures (ZnS QD-PEA) with the hydrodynamic diameter (

Identifiers

PMID30556011
PMCPMC6288785
OpenAlexW2900472188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.