Evidence map›Paper›PMID 30555976›Full record

ArticleJournal of current ophthalmology2018

Autoimmune keratitis in mycobacterium tuberculosis.

Parviz Rafiezadeh, Ingo Schmack, Mehdi Shajari, Thomas Kohnen

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of current ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Ocular mycobacterial lesions in cats.Veterinary pathology · 2022
    Article
  3. Article
  4. Article
  5. Peripheral Ulcerative Keratitis: A Review.Journal of ophthalmic & vision research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Parviz RafiezadehDepartment of Ophthalmology, Goethe-University, Frankfurt, Germany.
Ingo SchmackDepartment of Ophthalmology, Goethe-University, Frankfurt, Germany.
Mehdi ShajariDepartment of Ophthalmology, Goethe-University, Frankfurt, Germany.
Thomas KohnenDepartment of Ophthalmology, Goethe-University, Frankfurt, Germany.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a case of autoimmune keratitis in a patient with mycobacterium tuberculosis (MBT).

methodsAn 84-year-old male with pulmonary tuberculosis (TB) was admitted with chronic, non-healing bilateral ulcerations of the inferior peripheral cornea associated with stromal and subconjunctival nodules.

resultsClinical examination revealed circumscribed peripheral corneal ulceration with whitish nodules in adjacent stromal and subconjunctival tissue. Microbiological cultures of the corneal tissue were negative for MBT and other microbial pathogens; however, enzyme-linked immunosorbent assay (ELISA) of blood and corneal samples showed significantly elevated levels of IgM and IgA against MBT. In addition to systemic anti-tuberculosis therapy, the patient was treated topically with Polyspectran

conclusionThe present report demonstrates that MBT is able to initiate delayed autoimmune response within the corneal tissue during an intensive phase of anti-tuberculosis treatment.

Indexed as

Autoimmune responseOcular tuberculosisPhlyctenuleScrofulous keratitis

Identifiers

PMID30555976
PMCPMC6276618
OpenAlexW2804094797

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.