ArticleJournal of current ophthalmology2018
Risk of Parkinson's disease in patients with neovascular age-related macular degeneration.
Article in Journal of current ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 18 citations in OpenAlex.
- Protective effect of zinc against A2E-induced toxicity in ARPE-19 cells: Possible involvement of lysosomal acidification.Heliyon · 2024Article
- Incidence and risk factors of age-related macular degeneration in patients with Parkinson's disease: a population-based study.Frontiers in aging neuroscience · 2024Article
- Increased risk of Parkinson's disease among patients with age-related macular degeneration.BMC ophthalmology · 2021Article
- Seeing ophthalmologic problems in Parkinson disease: Results of a visual impairment questionnaire.Neurology · 2020Observational
- Self-reported visual dysfunction in Parkinson disease: the Survey of Health, Ageing and Retirement in Europe.European journal of neurology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine the risk of developing Parkinson's Disease (PD) in patients who are newly diagnosed with neovascular age-related macular degeneration (nAMD).
methodsThis was a cohort study using the British Columbia (BC) Retinal Disease Database. Data from 2009 to 2013 was accessed. Rates of PD in patients prior to the diagnosis of nAMD were computed and compared to the rates of patients newly diagnosed with PD after the diagnosis of nAMD.
resultsThe rate of PD prior to the diagnosis of nAMD was 1.42 per 100,000 person-years. The rate of PD after the diagnosis of nAMD was 2.88/100,000 person-years. The rate ratio was 2.03 (95% CI; 1.31-3.16).
conclusionsThe findings suggest that patients who are diagnosed with nAMD are at a significantly higher risk of developing PD later in life. More studies are needed to identify the pathological mechanism between the two diseases.
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