ArticleeNeurologicalSci2019
Pituitary metastasis of breast cancer mimicking IgG4-related hypophysitis.
Article in eNeurologicalSci, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Increased risk of breast cancer among premenopausal women with pituitary gland disorders in Taiwan: a population-based matched-cohort study.Journal of endocrinological investigation · 2025Article
- Solitary pituitary metastasis from breast cancer masquerading as a pituitary macroadenoma: a report of 2 rare cases.Gland surgery · 2024Article
- A case of pituitary metastasis discovered when diabetes insipidus developed in a patient 20 years after breast cancer treatment.Radiology case reports · 2023Article
- Early and isolated breast cancer metastasis to the pituitary: A case report and systematic review.Surgical neurology international · 2022Article
- Case Report: Pituitary metastasis as a presenting manifestation of silent gastric cardia adenocarcinoma.Frontiers in oncology · 2022Article
- Rare sites of breast cancer metastasis: a review.Translational cancer research · 2019Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IgG4-related hypophysitis, which is the pituitary gland inflammation caused by IgG4 positive lymphocytes, can affect cavernous sinus and orbital apex leading to developing cranial nerve related symptoms such as orbital apex syndrome (OAS). Here we report a case of hypopituitarism associated with OAS caused by pituitary metastasis of the breast cancer with elevated serum IgG4 level, who initially resembled to IgG4-related hypophysitis. Although this case had some features in common with igG4-related hypophysitis. The symptoms and pituitary enlargement were typical. However, steroid treatment did not improve her symptoms. Thus, we performed a tissue biopsy. Histopathologic examination of the hypophyseal tumor confirmed metastatic breast cancer in her pituitary. Pituitary metastatic tumor should be suspected if a case with OAS was once diagnosed as a cancer.
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