Evidence map›Paper›PMID 30555893›Full record

ArticleACS biomaterials science & engineering2018

Latent, Immunosuppressive Nature of Poly(lactic-

Riley P Allen, Amir Bolandparvaz, Jeffrey A Ma, Vishal A Manickam, Jamal S Lewis

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 105 citations in OpenAlex.

  1. Review
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  9. Unlocking Transplant Tolerance with Biomaterials.Advanced healthcare materials · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Engineering metabolism to modulate immunity.Advanced drug delivery reviews · 2024
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Riley P AllenDepartment of Biomedical Engineering, University of California Davis, 1 Shields Avenue, Davis, California 95616, United States.
Amir BolandparvazDepartment of Biomedical Engineering, University of California Davis, 1 Shields Avenue, Davis, California 95616, United States.
Jeffrey A MaDepartment of Biomedical Engineering, University of California Davis, 1 Shields Avenue, Davis, California 95616, United States.
Vishal A ManickamDepartment of Biomedical Engineering, University of California Davis, 1 Shields Avenue, Davis, California 95616, United States.
Jamal S LewisDepartment of Biomedical Engineering, University of California Davis, 1 Shields Avenue, Davis, California 95616, United States.
University of California, Davis · US

Funding

Animal Models of Infectious Diseases Training ProgramT32AI060555 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI MCSORLEY, STEPHEN J · 2004 to 2025
$3.3M
Leveraging Engineering Approaches to understand Cryptococcal Vomocytosis from Immune CellsR35GM125012 · NIGMS · UNIVERSITY OF FLORIDA · PI Jamal S Lewis · 2017 to 2026
$3.2M
NIAID NIH HHS T32 AI060555NIGMS NIH HHS R35 GM125012
6 · The paper itself

Abstract

Use of biomaterials to spatiotemporally control the activation of immune cells is at the forefront of biomedical engineering research. As more biomaterial strategies are employed for immunomodulation, understanding the immunogenicity of biodegradable materials and their byproducts is paramount in tailoring systems for immune activation or suppression. Poly(D,L-lactic-

Indexed as

dendritic cellsimmunogenicitylactic acidmicroparticlespoly(lactic-co-glycolic) acid

Identifiers

PMID30555893
PMCPMC6290919
OpenAlexW2786063237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.