Evidence map›Paper›PMID 30555839›Full record

ArticleIranian journal of biotechnology2018

Development of a Novel Gene Expression System for Secretory Production of Heterologous Proteins via the General Secretory (Sec) Pathway in

Huimin Jia, Hedan Li, Lirong Zhang, Daqing Xu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Recombinant Protein Expression System inFrontiers in microbiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Huimin JiaCollege of Life Sciences, Agricultural University of Hebei, Baoding 071001, China.
Hedan LiCollege of Life Sciences, Agricultural University of Hebei, Baoding 071001, China.
Lirong ZhangBiological Control Centre of Plant Diseases and Pests of Hebei, Agricultural University of Hebei, Baoding 071001, China.
Daqing XuCollege of Life Sciences, Agricultural University of Hebei, Baoding 071001, China.
Hebei Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

objectivesIn this study, a novel and efficient general secretory (Sec) pathway-dependent type gene expression system for the production of heterologous proteins was developed in MATERIALS AND

methodsThe synthesized cloning/expression cassette C was assembled into the basic

resultsThe vector pAU5 was successfully constructed. The SDS-PAGE experiment showed the AmyE protein band could be observed in the original culture supernatant of the 14067/pAU5-

conclusionsA novel efficient Sec-dependent type gene expression vector pAU5 was constructed in the

Indexed as

Corynebacterium glutamicumGene expression systemGeneral secretory (Sec) pathwayProtein secretion

Identifiers

PMID30555839
PMCPMC6217267
OpenAlexW2789399184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.