Evidence map›Paper›PMID 30555689›Full record

ArticleAntimicrobial resistance and infection control2018

Alarming levels of antimicrobial resistance among sepsis patients admitted to ICU in a tertiary care hospital in India - a case control retrospective study.

D Nagarjuna, Gajanand Mittal, Rakesh Singh Dhanda, Rajni Gaind, Manisha Yadav

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Frontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

D Nagarjuna1Dr. B. R. Ambedkar Centre for Biomedical Research (ACBR), University of Delhi (North Campus), Delhi, 110007 India.
Gajanand MittalDepartment of Microbiology, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital, Delhi, 110029 India.
Rakesh Singh DhandaStem Cell Laboratory, Longboat Explorers AB, SMiLE Incubator, Scheelevägen 2, 22381 Lund, Sweden.
Rajni GaindDepartment of Microbiology, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital, Delhi, 110029 India.
Manisha Yadav1Dr. B. R. Ambedkar Centre for Biomedical Research (ACBR), University of Delhi (North Campus), Delhi, 110007 India.ORCID 0000-0002-4771-4671
Vardhman Mahavir Medical College & Safdarjung Hospital · INAmbedkar University Delhi · INUniversity of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hospital acquired infections (HAI) are principal threats to the patients of intensive care units. An increase in the antimicrobial resistance (AMR) observed in gram negative bacteria is a great challenge to deal with. HAI and AMR lead to prolonged hospitalization and additional doses of anti-microbial treatment affecting patient's fitness and finances. Present study was undertaken to determine the pathotypes, genetic diversity and the antimicrobial resistance of Methods: Results: Pathotypes analysis revealed 46 and 16% of the blood Conclusion: The antimicrobial resistant profile found in this study is alarming and poses a great threat to public health. Apparently an increased antimicrobial resistance to the extensively used cephalosporins is affecting an optimal drug therapy for patients. In addition, the presence of catheters, prolonged duration of stay in the hospital and poor hygienic conditions due to infrequent urination of the patient can lead to an additional vulnerability. Therefore continuous surveillance and rational use of antibiotics along with effective hygienic measures are urgently recommended in such settings.

Indexed as

Drug Resistance, BacterialHospitalizationIntensive Care UnitsTertiary Care CentersAdhesins, BacterialAnti-Bacterial Agentsbeta-LactamasesCase-Control StudiesCephalosporinsCross InfectionDisk Diffusion Antimicrobial TestsEnterobacteriaceaeEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFecesAdhesins, BacterialAnti-Bacterial Agentsbeta-lactamase CTX-M-15beta-LactamasesCephalosporinsCTX-M-9 protein, E coliEscherichia coli ProteinsAntimicrobial resistance (AMR)Enterobacterial repeated intergenic consensus (ERIC)Escherichia coliIntensive care unit (ICU)PathotypesSepsis

Identifiers

PMID30555689
PMCPMC6286518
OpenAlexW2903713991

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.