Evidence map›Paper›PMID 30555680›Full record

ArticleClinical and translational allergy2018

Dual exposure to smoking and household air pollution is associated with an increased risk of severe asthma in adults in Brazil.

Andréia Guedes Oliva Fernandes, Carolina de Souza-Machado, Gabriela Pimentel Pinheiro, Sergio Telles de Oliva, Raquel Cristina Lins Mota, Valmar Bião de Lima, Constança Sampaio Cruz, José Miguel Chatkin, Álvaro A Cruz

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational allergy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Asthma and Tobacco Smoking.Journal of personalized medicine · 2022
    Review
  6. Association of quality of life and disease control with cigarette smoking in patients with severe asthma.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Article
  7. Article
  8. Article
  9. Impact of Air Pollution on Asthma Outcomes.International journal of environmental research and public health · 2020
    Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Andréia Guedes Oliva Fernandes1Programa para o Controle da Asma na Bahia (ProAR) e Programa de Pós-graduação em Medicina e Saúde, Centro de Saúde Carlos Gomes, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (UFBA), Rua Carlos Gomes 270, 7° andar, Salvador, Bahia 40060-330 Brazil.
Carolina de Souza-Machado2Programa para o Controle da Asma na Bahia (ProAR) e Programa de Pós-graduação em Medicina e Saúde, Faculdade de Medicina da Bahia, Escola de Enfermagem da Universidade Federal da Bahia, UFBA, Rua Dr Augusto Vianna. 2 andar. Campus Canela, Salvador, Bahia 40110-060 Brazil.
Gabriela Pimentel Pinheiro1Programa para o Controle da Asma na Bahia (ProAR) e Programa de Pós-graduação em Medicina e Saúde, Centro de Saúde Carlos Gomes, Faculdade de Medicina da Bahia, Universidade Federal da Bahia (UFBA), Rua Carlos Gomes 270, 7° andar, Salvador, Bahia 40060-330 Brazil.
Sergio Telles de Oliva3Laboratório de Química Analítica Ambiental, Departamento de Química Analítica, Instituto de Química, Universidade Federal da Bahia, Brazil, Rua Barão de Jeremoabo, 147. Campus de Ondina, Salvador, Bahia 40170-115 Brazil.
Raquel Cristina Lins Mota4Serviço de Endoscopia Digestiva do Hospital das Clínicas de Universidade de São Paulo, PAMB, Prédio dos Ambulatórios, Av. Dr. Enéas Carvalho de Aguiar, 155 - 6°. Andar, Sala 3, São Paulo, SP CEP 05403-900 Brazil.
Valmar Bião de Lima5Programa para o Controle da Asma na Bahia (ProAR), UFBA - Centro de Saúde Carlos Gomes, Rua Carlos Gomes 270, 7° andar, Salvador, Bahia 40060-330 Brazil.
Constança Sampaio CruzPrograma de Pós-Graduação em Medicina e Saúde Humana. Escola Bahiana de Medicina e Saúde Pública (EBMSP), Obras Sociais Irmã Dulce. Hospital Santo Antônio - Avenida Bonfim, 161 Largo de Roma, Salvador, Bahia 40420-415 Brazil.
José Miguel Chatkin7Escola de Medicina da Pontifícia, Universidade Católica do Rio Grande do Sul, Brazil, Av. Ipiranga, 6690, Porto Alegre, Rio Grande do Sul 90610-000 Brazil.
Álvaro A Cruz5Programa para o Controle da Asma na Bahia (ProAR), UFBA - Centro de Saúde Carlos Gomes, Rua Carlos Gomes 270, 7° andar, Salvador, Bahia 40060-330 Brazil.
Universidade Federal da Bahia · BREscola Bahiana de Medicina e Saúde Pública · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRPontifícia Universidade Católica do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between smoking, household pollution, dual exposure and severity of asthma in adults has not been sufficiently studied. We examined and compared the effects of cigarette smoking, domestic wood burning pollution and dual exposure (tobacco and wood burning) upon asthma severity in adults.

methodsThis was a cross-sectional study performed with 452 individuals with mild to moderate asthma and 544 patients with severe asthma (previously untreated). Smoking and exposure to wood smoke were identified and quantified through questionnaires to evaluate current and/or previous exposure; objective determination of cigarette exposure was obtained through the measurement of urinary cotinine. Asthma control was evaluated through Asthma Control Questionnaire; and severity was classified according to the Global Initiative for Asthma criteria. Subjects were grouped according to exposure type into 4 groups: smokers, household pollution, dual-exposure and no-exposure. Chi square, Mann-Whitney, and Kruskal-Wallis tests were used for comparisons between groups.

resultsOut of 996 included individuals, 78 (7.8%) were exposed to cigarette smoking alone, 358 (35.9%) to household pollution alone, 155 (15.6%) to the two exposures combined and 405 (40.7%) were not exposed. Compared to unexposed individuals, exposure to household pollution resulted in poorer asthma control, higher proportion of severe asthma, and worse indicators of lung function. The double-exposed individuals were worse off in all the evaluated parameters, and they were significantly worse than subjects with single exposure to household air pollution in relation to asthma severity and lung function. These subjects were predominantly females, older, with longer residence time in rural areas, lower income and lower schooling levels. Multivariate analysis showed that exposure to household pollution and double exposure were predictive factors associated with lack of control and increased severity of asthma.

conclusionsExposure to household pollution is associated with poorer control, greater severity, and poorer pulmonary function; double-exposed individuals have a greater risk of severe asthma and decreased lung function than those exposed only to household pollution.

Indexed as

Air pollution indoorsAsthmaControlSeveritySmoking

Identifiers

PMID30555680
PMCPMC6287342
OpenAlexW2901568290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.