Evidence map›Paper›PMID 30555635›Full record

ArticleOncotarget2018

Diagnostic performance of Gd-EOB-DTPA-enhanced MRI for evaluation of liver dysfunction: a multivariable analysis of 3T MRI sequences.

Niklas Verloh, Kirsten Utpatel, Florian Zeman, Claudia Fellner, Hans J Schlitt, Martina Müller, Christian Stroszczynski, Matthias Evert, Philipp Wiggermann, Michael Haimerl

Abstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Niklas VerlohDepartment of Radiology, University Hospital Regensburg, Regensburg, Germany.
Kirsten UtpatelDepartment of Pathology, University Regensburg, Regensburg, Germany.
Florian ZemanCenter for Clinical Trials, University Hospital Regensburg, Regensburg, Germany.
Claudia FellnerDepartment of Radiology, University Hospital Regensburg, Regensburg, Germany.
Hans J SchlittDepartment of Surgery, University Hospital Regensburg, Regensburg, Germany.
Martina MüllerDepartment of Internal Medicine I, Gastroenterology, Endocrinology, Rheumatology, and Infectious Diseases, Regensburg University Hospital, Regensburg, Germany.
Christian StroszczynskiDepartment of Radiology, University Hospital Regensburg, Regensburg, Germany.
Matthias EvertDepartment of Pathology, University Regensburg, Regensburg, Germany.
Philipp WiggermannDepartment of Radiology, University Hospital Regensburg, Regensburg, Germany.
Michael HaimerlDepartment of Radiology, University Hospital Regensburg, Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate the diagnostic performance of a multiparametric gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MRI examination for the estimation of liver dysfunction classified by the Model for End-Stage Liver Disease (MELD) score.

resultsLiver dysfunction can be assessed by different methods. In a logistic regression analysis, T1- and T2-weighted images were affected by impaired liver function. In the assessment of liver dysfunction, the reduction rate in T1 mapping sequences showed a significant correlation in simple and multiple logistic regression.

conclusionChanges in Gd-EOB-DTPA-enhanced MRI between plain images and images obtained during the hepatobiliary phase allowed good prediction of liver dysfunction, especially when using T1 mapping sequences. MATERIALS AND

methodsA total of 199 patients underwent contrast-enhanced MRI with a hepatocyte-specific contrast agent at 3T. In the multivariable analysis, the full range of available MRI sequences was used to estimate the liver dysfunction of patients with various MELD scores.

Indexed as

abdomenlivermagnetic resonance imagingMELD scoremultiparametric examination

Identifiers

PMID30555635
PMCPMC6284745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.