Evidence map›Paper›PMID 30555632›Full record

ArticleOncotarget2018

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis.

Wei Sha, Yanfei Zhou, Zhi-Qiang Ling, Guiqin Xie, Xiaowu Pang, Paul Wang, Xinbin Gu

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Emerging Roles of Ceramides in Breast Cancer Biology and Therapy.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Article
  7. Frontiers in pharmacology · 2022
    Review
  8. Salvianolic acid B fromFrontiers in pharmacology · 2022
    Review
  9. Article
  10. Bioactive constituents ofPharmaceutical biology · 2020
    Article
  11. Possible applications of salvianolic acid B against different cancers.Exploration of targeted anti-tumor therapy · 2020
    Review
  12. Review
  13. Methanol Extract ofInternational journal of food science · 2020
    Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Wei ShaDepartments of Oral Pathology, College of Dentistry, Howard University, Washington, D.C., USA.
Yanfei ZhouTenGen Biomedical Co., Bethesda, Maryland, USA.
Zhi-Qiang LingZhejiang Cancer Hospital, Zhejiang Cancer Research Institute, Hangzhou, Zhejiang, China.
Guiqin XieDepartments of Oral Pathology, College of Dentistry, Howard University, Washington, D.C., USA.
Xiaowu PangDepartments of Oral Pathology, College of Dentistry, Howard University, Washington, D.C., USA.
Paul WangDepartment of Radiology, College of Medicine, Howard University, Washington, D.C., USA.
Xinbin GuDepartments of Oral Pathology, College of Dentistry, Howard University, Washington, D.C., USA.
Howard University · USZhejiang Cancer Hospital · CN

Funding

PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
Train-Edu-Prog, Collaborative Cancer Research Training and Education Program Leading to Minority InitiativeP20CA192989 · NCI · HOWARD UNIVERSITY · PI GU, XINBIN · 2014 to 2017
$801k
NCI NIH HHS P20 CA192989NIMHD NIH HHS G12 MD007597
6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited treatment options. It is urgent to develop new therapeutics against this disease. Salvinolic acid B (Sal-B) is a leading bioactive component of Salvia

Indexed as

apoptosisceramidesglucosylceramide synthasesalvianolic acid Btriple negative breast cancer

Identifiers

PMID30555632
PMCPMC6284743
OpenAlexW2901882667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.