Evidence map›Paper›PMID 30555604›Full record

ArticleJournal of arrhythmia2018

Effect of epicardial fat and metabolic syndrome on reverse atrial remodeling after ablation for atrial fibrillation.

Koyuru Monno, Yasuo Okumura, Yuki Saito, Yoshihiro Aizawa, Koichi Nagashima, Masaru Arai, Ryuta Watanabe, Yuji Wakamatsu, Naoto Otsuka, Shunichi Yoda and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Koyuru MonnoDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.ORCID 0000-0002-9502-5061
Yasuo OkumuraDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Yuki SaitoDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Yoshihiro AizawaDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Koichi NagashimaDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Masaru AraiDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Ryuta WatanabeDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.ORCID 0000-0003-2664-7139
Yuji WakamatsuDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Naoto OtsukaDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Shunichi YodaDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Takafumi HiroDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Ichiro WatanabeDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Atsushi HirayamaDivision of Cardiology Department of Medicine Nihon University School of Medicine Tokyo Japan.
Nihon University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic syndrome/epicardial adipose tissue (EAT) plays an important role in atrial fibrillation (AF). Although reverse atrial remodeling (RAR) often occurs after AF ablation, the effects of EAT on RAR remain unknown.

methodsStudy subjects were 104 patients in whom transthoracic echocardiography (TTE) was performed before AF ablation and 3, 6, and 12 months afterward. EAT was assessed in terms of its thickness adjacent to the right ventricular anterior wall in the TTE parasternal view. RAR was defined as >10% reduction in the left atrial volume (LAV) index by the 3-month follow-up examination.

resultsPostablation RAR occurred in 57/104 (55%) patients. RAR absence was associated with a relatively thick EAT (4.92 ± 1.65 vs. 3.92 ± 1.17 mm,

conclusionsEAT and metabolic syndrome appear to be strongly associated with RAR absence, but only the thick EAT was significantly associated with the postablation AF recurrence. Our findings, especially the thinning of EAT, suggest that thick EAT lead to AF vulnerability but that EAT reduction favorably affects ablation outcome.

Indexed as

atrial fibrillationatrial remodelingechocardiographyepicardial adipose tissuemetabolic syndrome

Identifiers

PMID30555604
PMCPMC6288560
OpenAlexW2896579843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.