Evidence map›Paper›PMID 30555569›Full record

ArticleTheranostics2018

Engineered RNase P Ribozymes Effectively Inhibit the Infection of Murine Cytomegalovirus in Animals.

Wei Li, Yujun Liu, Yuanyuan Wang, Ruilin Li, Phong Trang, Wei Tang, Zhu Yang, Yu Wang, Xu Sun, Xiwen Xing and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Wei LiDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China.
Yujun LiuSchool of Public Health, University of California, Berkeley, CA 94720.
Yuanyuan WangDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China.
Ruilin LiDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China.
Phong TrangSchool of Public Health, University of California, Berkeley, CA 94720.
Wei TangSchool of Public Health, University of California, Berkeley, CA 94720.
Zhu YangJiangsu Affynigen Biotechnolgies Inc, Taizhou, Jiangsu 225300, China.
Yu WangDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China.
Xu SunDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China.
Xiwen XingDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China.
Sangwei LuSchool of Public Health, University of California, Berkeley, CA 94720.
Fenyong LiuDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China.
Jinan University · CNUniversity of California, Berkeley · USGuangzhou Experimental Station · CN

Funding

RIBOZYMES FOR STUDIES AND TREATMENT OF HCMV INFECTIONSR01AI041927 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI LIU, FENYONG · 1997 to 2012
$3.7M
Persistent infection of human cytomegalovirus in oral mucosaR01DE025462 · NIDCR · UNIVERSITY OF CALIFORNIA BERKELEY · PI LIU, FENYONG · 2015 to 2019
$2.3M
Human cytomegalovirus chromatin modifications in oral infectionR01DE023935 · NIDCR · UNIVERSITY OF CALIFORNIA BERKELEY · PI LIU, FENYONG · 2013 to 2017
$2.3M
Bacteria Based Agents for Therapy of AIDS Associated InfectionsR01AI091536 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI LU, SANGWEI · 2011 to 2014
$1.3M
NIAID NIH HHS R01 AI041927NIAID NIH HHS R01 AI091536NIDCR NIH HHS R01 DE023935NIDCR NIH HHS R01 DE025462
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCytomegalovirusGenetic TherapyMiceMuromegalovirusRibonuclease PRNA, AntisenseRNA, CatalyticRNA, MessengerRibonuclease PRNA, AntisenseRNA, CatalyticRNA, Messengerantisense RNAantiviralgene targetinggene therapyribozyme

Identifiers

PMID30555569
PMCPMC6276291
OpenAlexW2903411772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.