Evidence map›Paper›PMID 30555558›Full record

ArticleTheranostics2018

"Cell-addictive" dual-target traceable nanodrug for Parkinson's disease treatment via flotillins pathway.

YanHui Li, ZiXuan Chen, ZhiGuo Lu, QingHu Yang, LinYing Liu, ZhaoTan Jiang, LiQun Zhang, Xin Zhang, Hong Qing

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
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  8. Multifunctional nanomedicine strategies to manage brain diseases.Drug delivery and translational research · 2023
    Review
  9. Review
  10. Nucleic acid drug vectors for diagnosis and treatment of brain diseases.Signal transduction and targeted therapy · 2023
    Review
  11. Review
  12. Protein clearance strategies for disease intervention.Journal of neural transmission (Vienna, Austria : 1996) · 2022
    Review
  13. Review
  14. Review
  15. Review
  16. Article
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

YanHui LiSchool of Life Science, Beijing Institute of Technology, Beijing 100081, PR China.
ZiXuan ChenSchool of Life Science, Beijing Institute of Technology, Beijing 100081, PR China.
ZhiGuo LuState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, PR China.
QingHu YangSchool of Life Science, Beijing Institute of Technology, Beijing 100081, PR China.
LinYing LiuState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, PR China.
ZhaoTan JiangSchool of Life Science, Beijing Institute of Technology, Beijing 100081, PR China.
LiQun ZhangBeijing Chest Hospital, Capital Medical University, Beijing 101149, PR China.
Xin ZhangState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, PR China.
Hong QingSchool of Life Science, Beijing Institute of Technology, Beijing 100081, PR China.
Beijing Institute of Technology · CNInstitute of Process Engineering · CNBeijing Chest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-synclein (αS) aggregation is a representative molecular feature of the pathogenesis of Parkinson's disease (PD). Epigallocatechin gallate (EGCG) can prevent αS aggregation

Indexed as

alpha-SynucleinAnimalsAnimals, Genetically ModifiedCatechinCell LineDisease Models, AnimalDopaminergic NeuronsDrug CarriersHumansMembrane ProteinsMiceMolecular Targeted TherapyNanoparticlesNeuroprotective AgentsParkinson DiseaseProtein Aggregation, Pathologicalalpha-SynucleinCatechinDrug Carriersepigallocatechin gallateflotillinsMembrane ProteinsNeuroprotective Agentsdopaminergic neuronsEGCGnanoparticlesParkinson's diseaseα-synclein aggregation

Identifiers

PMID30555558
PMCPMC6276100
OpenAlexW2898621078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.