Evidence map›Paper›PMID 30555555›Full record

ArticleTheranostics2018

Exosomal microRNA-21 derived from bronchial epithelial cells is involved in aberrant epithelium-fibroblast cross-talk in COPD induced by cigarette smoking.

Hui Xu, Min Ling, Junchao Xue, Xiangyu Dai, Qian Sun, Chao Chen, Yi Liu, Liang Zhou, Jianping Liu, Fei Luo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 2 syntheses or guidelines pooled it, 209 citations in OpenAlex.

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  5. Hallmarks of the ageing lung: 10 years later.The European respiratory journal · 2026
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68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Hui XuInstitute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.
Min LingJiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu, People's Republic of China.
Junchao XueInstitute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.
Xiangyu DaiInstitute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.
Qian SunInstitute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.
Chao ChenInstitute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.
Yi LiuInstitute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.
Liang ZhouLiyang Center for Disease Control and Prevention, Liyang 213300, Jiangsu, People's Republic of China.
Jianping LiuLiyang Center for Disease Control and Prevention, Liyang 213300, Jiangsu, People's Republic of China.
Fei LuoFaculty of Public Health, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, People's Republic of China.
Qian BianJiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu, People's Republic of China.
Qizhan LiuInstitute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell CommunicationAnimalsCell DifferentiationCells, CulturedCigarette SmokingCoculture TechniquesCulture MediaDisease Models, AnimalEpithelial CellsEpitheliumExosomesFibroblastsHumansHypoxia-Inducible Factor 1, alpha SubunitMice, Inbred BALB CMicroRNAsCulture MediaHypoxia-Inducible Factor 1, alpha SubunitMicroRNAsMIRN21 microRNA, humanMIRN21 microRNA, mouseVHL protein, humanVHL protein, mouseVon Hippel-Lindau Tumor Suppressor Proteinairway remodelingcigarette smokingCOPDexosomemicroRNA

Identifiers

PMID30555555
PMCPMC6276085
OpenAlexW2898749924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.