ArticleTheranostics2018
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
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In one paragraph
Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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0cells of the map it votes in
43citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
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Who cites it
43 citing papers in PubMed, 65 citations in OpenAlex.
- Immune cell dynamics in neurological disorders: from inflammation to microgliopathy and Neuron-Glia crosstalk.Molecular biology reports · 2026Review
- Shared Neuroinflammatory Mechanisms Across Dementia Types: An Integrative Review.International journal of molecular sciences · 2025Review
- Exploration of Fluorinated Pyrazolidine-3,5-Diones for Positron Emission Tomography Imaging of the P2YChemMedChem · 2025Article
- Design, Synthesis and Preclinical Evaluation of a Brain-Permeable PET Tracer for P2Y12 Receptor Imaging in the Brain.Journal of medicinal chemistry · 2025Article
- Targeting CX3CR1 Signaling Dynamics: A Critical Determinant in the Temporal Regulation of Post-Stroke Neurorepair.Brain sciences · 2025Review
- Drug-like Antagonists of P2Y Receptor Subtypes: An Update.Journal of medicinal chemistry · 2025Review
- Neuroinflammation in Alzheimer disease.Nature reviews. Immunology · 2025Review
- Synthesis, preclinical evaluation and pilot clinical study of a P2YActa pharmaceutica Sinica. B · 2025Article
- PET imaging of neuroinflammation: any credible alternatives to TSPO yet?Molecular psychiatry · 2025Review
- Curcumin/pEGCG-encapsulated nanoparticles enhance spinal cord injury recovery by regulating CD74 to alleviate oxidative stress and inflammation.Journal of nanobiotechnology · 2024Article
- The Brain-Gut Axis, an Important Player in Alzheimer and Parkinson Disease: A Narrative Review.Journal of clinical medicine · 2024Review
- Weisheng-tang protects against ischemic brain injury by modulating microglia activation through the P2Y12 receptor.Frontiers in pharmacology · 2024Article
- Microglial Positron Emission Tomography Imaging In Vivo : Positron Emission Tomography Radioligands: Utility in Research and Clinical Practice.Advances in neurobiology · 2024Review
- Non-invasiveFrontiers in cellular neuroscience · 2024Review
- Integrative Analysis of Single-Cell and Bulk Sequencing Data Depicting the Expression and Function of P2ry12 in Microglia Post Ischemia-Reperfusion Injury.International journal of molecular sciences · 2023Article
- Positron Emission Tomography of Neuroimmune Responses in Humans: Insights and Intricacies.Seminars in nuclear medicine · 2023Review
- Characterization of microglia behaviour in healthy and pathological conditions with image analysis tools.Open biology · 2023Article
- Diagnostic and therapeutic value of P2Y12R in epilepsy.Frontiers in pharmacology · 2023Review
- Imaging in translational cancer research.Cancer biology & medicine · 2022Review
- PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
27 authors at 13 institutions in 9 countries.
Alessandro VillaCenter of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Barbara KleinInstitute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.
Bieneke JanssenDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands.
Jordi PedragosaInstitut d'Investigacions Biomèdiques Agustí Pi i Sunyer, Barcelona, Spain.
Giovanna PepeCenter of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Bastian ZinnhardtEuropean Institute for Molecular Imaging (EIMI), University of Münster, Münster, Germany.
Danielle J VugtsDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands.
Paolo GelosaCentro Cardiologico Monzino IRCCS, Milan, Italy.
Luigi SironiCenter of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Wissam BeainoDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands.
Annelaure DamontIMIV, Service Hospitalier Frédéric Joliot, CEA, Inserm, Université Paris Sud, CNRS, Université Paris-Saclay, Orsay, France.
Frédéric DolléIMIV, Service Hospitalier Frédéric Joliot, CEA, Inserm, Université Paris Sud, CNRS, Université Paris-Saclay, Orsay, France.
Benoit JegoIMIV, Service Hospitalier Frédéric Joliot, CEA, Inserm, Université Paris Sud, CNRS, Université Paris-Saclay, Orsay, France.
Alexandra WinkelerIMIV, Service Hospitalier Frédéric Joliot, CEA, Inserm, Université Paris Sud, CNRS, Université Paris-Saclay, Orsay, France.
Dieter OryLaboratory for Radiopharmacy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Olof SolinRadiopharmaceutical Chemistry Laboratory, Turku PET Centre, University of Turku, Turku, Finland.
Johnny VercouillieUMRS Inserm U930 - Université de Tours, Tours France.
Uta FunkeDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands.
Sandra Laner-PlambergerSpinal Cord Injury and Tissue Regeneration Center (SCI-TReCS), Paracelsus Medical University, Salzburg, Austria.
Linda V BlomsterSaniona A/S, Ballerup, Denmark.
Palle ChristophersenSaniona A/S, Ballerup, Denmark.
Elisabetta VegetoCenter of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Ludwig AignerInstitute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.
Andreas JacobsEuropean Institute for Molecular Imaging (EIMI), University of Münster, Münster, Germany.
Anna M PlanasInstitut d'Investigacions Biomèdiques Agustí Pi i Sunyer, Barcelona, Spain.
Adriana MaggiCenter of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Albert D WindhorstDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands.
Amsterdam Neuroscience · NLUniversity of Milan · ITSaniona (Denmark) · DKConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESInserm · FRParacelsus Medical University · ATUniversity of Münster · DECEA Paris-Saclay · FRCentre National de la Recherche Scientifique · FRCentro Cardiologico Monzino · ITKU Leuven · BEUniversité Paris-Saclay · FRUniversity of Turku · FI
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microglia are potential targets for therapeutic intervention in neurological and neurodegenerative diseases affecting the central nervous system. In order to assess the efficacy of therapies aimed to reduce the tissue damaging activities of microglia and/or to promote the protective potential of these cells, suitable pre-clinical and clinical tools for the
Indexed as
AnimalsAnti-Inflammatory AgentsBrainCarbon RadioisotopesComputational BiologyGene Expression ProfilingHumansImmunohistochemistryInterleukin-4MiceMicrogliaMolecular ImagingPositron-Emission TomographyRadioactive TracersReal-Time Polymerase Chain ReactionReceptors, Purinergic P2Y12Anti-Inflammatory AgentsCarbon RadioisotopesInterleukin-4Radioactive TracersReceptors, Purinergic P2Y12microglianeuroinflammationPET tracers.radiochemistrytranslational markers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.